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欧洲 ADHD 药物不良反应管理指南

European guidelines on managing adverse effects of medication for ADHD.

机构信息

Child and Adolescent Psychiatry, The Centre for Child Health, Dundee, UK.

出版信息

Eur Child Adolesc Psychiatry. 2011 Jan;20(1):17-37. doi: 10.1007/s00787-010-0140-6. Epub 2010 Nov 3.

Abstract

The safety of ADHD medications is not fully known. Concerns have arisen about both a lack of contemporary-standard information about medications first licensed several decades ago, and signals of possible harm arising from more recently developed medications. These relate to both relatively minor adverse effects and extremely serious issues such as sudden cardiac death and suicidality. A guidelines group of the European Network for Hyperkinetic Disorders (EUNETHYDIS) has therefore reviewed the literature, recruited renowned clinical subspecialists and consulted as a group to examine these concerns. Some of the effects examined appeared to be minimal in impact or difficult to distinguish from risk to untreated populations. However, several areas require further study to allow a more precise understanding of these risks.

摘要

多动症药物的安全性尚未完全明确。人们对以下两方面感到担忧:一方面,几十年前首次获得许可的药物缺乏当代标准信息;另一方面,最近开发的药物可能出现有害信号。这些信号涉及相对较小的不良反应,以及突然心脏死亡和自杀等极其严重的问题。因此,欧洲多动障碍网络(EUNETHYDIS)的一个指导小组审查了文献,招募了著名的临床亚专科医生,并集体咨询,以检查这些问题。一些被检查的影响似乎影响很小,或者难以与未治疗人群的风险区分开来。然而,一些领域需要进一步研究,以便更准确地了解这些风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12f8/3012210/f655aaa4303a/787_2010_140_Fig1_HTML.jpg

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