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美国九旬和百岁老人的初次膝关节和髋关节置换术。

Primary knee and hip arthroplasty among nonagenarians and centenarians in the United States.

作者信息

Krishnan Eswar, Fries James F, Kwoh C Kent

机构信息

University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA.

出版信息

Arthritis Rheum. 2007 Aug 15;57(6):1038-42. doi: 10.1002/art.22888.

Abstract

OBJECTIVE

The number of individuals ages >or=100 years in the US is expected to increase considerably in the future along with the need for arthroplasties. This report focuses on the poorly studied epidemiology and mortality outcomes of arthroplasty among these individuals.

METHODS

We describe the epidemiology of knee and hip arthroplasties among centenarians using data from a large hospital discharge database in the US (the Nationwide Inpatient Sample) during the period 1993 through 2002. We used nonagenarians as the comparison group with adjustment for differences in the prevalence of congestive heart failure, neurologic diseases such as dementia and stroke, renal and hepatic diseases, obesity, anemia, malignancy, coagulopathy, and depression and other psychiatric illnesses. Cox regression models were used to study the mortality outcomes following arthroplasty.

RESULTS

Overall, there were 679 hip arthroplasties and 7 knee arthroplasties among centenarians in this database. The corresponding figures for nonagenarians were 33,975 and 2,050, respectively. A vast majority (83%) of hip arthroplasty recipients were women. Risk-adjusted mortality estimates following arthroplasty for centenarians were higher than for nonagenarians (hazard ratio 1.46, 95% confidence interval 1.10-1.95). However, this was similar to differences in overall in-hospital mortality (hazard ratio 1.36, 95% confidence interval 1.32-1.40) between these 2 age categories.

CONCLUSION

In the US population, hip and knee arthroplasty are very rarely performed among centenarians. Our in-hospital mortality data suggest that arthroplasties should not be denied to centenarians solely because of short-term postoperative life expectancy estimates.

摘要

目的

随着关节置换术需求的增加,预计美国100岁及以上人群的数量在未来将大幅增长。本报告重点关注这部分人群中关节置换术研究较少的流行病学和死亡率结果。

方法

我们使用1993年至2002年期间美国一个大型医院出院数据库(全国住院患者样本)中的数据,描述百岁老人膝关节和髋关节置换术的流行病学情况。我们将九旬老人作为对照组,并对充血性心力衰竭、痴呆和中风等神经系统疾病、肾脏和肝脏疾病、肥胖、贫血、恶性肿瘤、凝血病以及抑郁症和其他精神疾病的患病率差异进行了调整。使用Cox回归模型研究关节置换术后的死亡率结果。

结果

总体而言,该数据库中百岁老人有679例髋关节置换术和7例膝关节置换术。九旬老人的相应数字分别为33975例和2050例。绝大多数(83%)髋关节置换术接受者为女性。百岁老人关节置换术后经风险调整的死亡率估计高于九旬老人(风险比1.46,95%置信区间1.10 - 1.95)。然而,这与这两个年龄组之间总体住院死亡率的差异相似(风险比1.36,95%置信区间1.32 - 1.40)。

结论

在美国人群中,百岁老人很少进行髋关节和膝关节置换术。我们的住院死亡率数据表明,不应仅仅因为术后短期预期寿命估计而拒绝为百岁老人进行关节置换术。

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