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非agenarians人群初次全髋关节或膝关节置换术后的临床结局。 注:这里“nonagenarians”可能有误,推测可能是“nonagenarian”,意为“九十多岁的人” 。如果是这样,完整译文为:九十多岁老人初次全髋关节或膝关节置换术后的临床结局。

Clinical outcome following primary total hip or knee replacement in nonagenarians.

作者信息

Skinner D, Tadros B J, Bray E, Elsherbiny M, Stafford G

机构信息

Elective Orthopaedic Centre , Epsom , UK.

出版信息

Ann R Coll Surg Engl. 2016 Apr;98(4):258-64. doi: 10.1308/rcsann.2016.0095. Epub 2016 Feb 29.

Abstract

Introduction The Elective Orthopaedic Centre in Epsom has an established patient reported outcome measures programme, into which all patients are enrolled. Postoperative complications, Oxford hip/knee scores (OHS/OKS) and EQ-5D™ (EuroQol, Rotterdam, Netherlands) scores are collected up to the second postoperative year. Our population is ageing and the number of joint replacements being performed on the very elderly is rising. The aim of this study was to investigate the outcome of joint replacements in a nonagenarian population. Methods Our dataset was reviewed retrospectively for a cohort of nonagenarians undergoing either a primary total hip replacement (THR) or total knee replacement (TKR) between April 2008 and October 2011. Postoperative complications, mortality rates and functional outcomes were compared with those of a time matched 70-79-year-old cohort. Results Nonagenarians requiring a THR presented with a lower preoperative OHS (p=0.020) but made a greater improvement in the first postoperative year than the younger cohort (p=0.040). The preoperative OKS was lower for nonagenarians than for the control group (p=0.022). At one and two years after TKR, however, there was no significant difference between the age groups. The nonagenarians had a greater risk of requiring a blood transfusion following both THR (p=0.027; 95% confidence interval [CI]: 1.11-5.75) and TKR (p=0.037; 95% CI: 1.08-16.65) while the latter cohort also required a longer stay than their younger counterparts (p=0.001). Mortality rates were higher in the nonagenarian group but these were in keeping with the life expectancy projections identified by the Office for National Statistics. Conclusions Over a two-year period, the functional outcome and satisfaction rates achieved by nonagenarians following a THR or TKR are comparable with 70-79-year-olds.

摘要

引言 埃普索姆的择期骨科中心有一个既定的患者报告结局测量项目,所有患者均已登记入组。收集术后并发症、牛津髋关节/膝关节评分(OHS/OKS)以及EQ-5D™(欧洲生活质量量表,荷兰鹿特丹)评分,直至术后第二年。我们的患者群体正在老龄化,针对高龄患者进行的关节置换手术数量正在增加。本研究的目的是调查非agenarian人群关节置换的结局。方法 我们对2008年4月至2011年10月期间接受初次全髋关节置换(THR)或全膝关节置换(TKR)的非agenarian队列的数据集进行了回顾性分析。将术后并发症、死亡率和功能结局与年龄匹配的70 - 79岁队列进行比较。结果 需要进行THR的非agenarian术前OHS较低(p = 0.020),但术后第一年的改善程度比年轻队列更大(p = 0.040)。非agenarian的术前OKS低于对照组(p = 0.022)。然而,在TKR术后一年和两年时,各年龄组之间没有显著差异。非agenarian在THR(p = 0.027;95%置信区间[CI]:1.11 - 5.75)和TKR(p = 0.037;95% CI:1.08 - 16.65)后需要输血的风险更高,而后一组队列的住院时间也比年轻患者更长(p = 0.001)。非agenarian组的死亡率较高,但这些与英国国家统计局确定的预期寿命预测相符。结论 在两年期间,非agenarian进行THR或TKR后的功能结局和满意度与70 - 79岁人群相当。

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