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医学重症监护病房患者的入院时间及治疗结果。

Admission time and outcomes of patients in a medical intensive care unit.

作者信息

Sheu Chau-Chyun, Tsai Jong-Rung, Hung Jen-Yu, Yang Chih-Jen, Hung Hsin-Chia, Chong Inn-Wen, Huang Ming-Shyan, Hwang Jhi-Jhu

机构信息

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.

出版信息

Kaohsiung J Med Sci. 2007 Aug;23(8):395-404. doi: 10.1016/S0257-5655(07)70003-2.

Abstract

Studies have shown that weekend or night admissions to intensive care units (ICUs) are associated with increased mortality in critically ill patients. Our study aimed to evaluate the effects of admission time and day on patient outcomes in a medical ICU equipped with patient management guide-lines, and staffed by intensivists on call for 24 hours, who led the morning rounds on all days of the week but did not stay in-house overnight. The study enrolled 611 consecutive patients admitted to a 26-bed medical ICU in a university hospital during a 7-month period. We divided them into two groups, which we labeled as "office hours" (08:00-18:00 on weekdays) and "non-office hours" (18:00-08:00 on weekdays, and all times on weekends) according to their ICU admission times. The clinical outcomes were compared between the groups. The effects of admission on weekends, at night, and various days of the week on hospital mortality were also evaluated. Our results showed that there were no significant differences in ICU and hospital mortalities between patients admitted during office hours and those admitted during non-office hours (27.2% vs. 27.4%, p = 1.000; 38.9% vs. 37.6%, p = 0.798). The ICU length of stay, ICU-free time within 21 days, and length of stay in the hospital were also comparable in both groups. Among the 392 patients requiring mechanical ventilation, the ventilator outcomes were not significantly different between those in the office-hour group and the non-office-hour group. Multivariate logistic regression analyses showed that the adjusted odds of hospital mortality were not significantly higher for patients admitted to our ICU on weekends, at night, or on any days of the week. In conclusion, our results showed that non-office-hour admissions to our medical ICU were not associated with poorer ICU, hospital, and ventilator outcomes, compared with office-hour admissions. Neither were time of day and day of the week admissions to our ICU associated with significant differences in hospital mortality.

摘要

研究表明,重症监护病房(ICU)在周末或夜间收治的重症患者死亡率较高。我们的研究旨在评估在配备患者管理指南、有24小时随叫随到的重症监护医生且每周每天都进行晨间查房但不住院过夜的内科ICU中,收治时间和日期对患者预后的影响。该研究纳入了一所大学医院26张床位的内科ICU在7个月期间连续收治的611例患者。我们根据他们的ICU收治时间将他们分为两组,分别标记为“办公时间”(工作日的08:00 - 18:00)和“非办公时间”(工作日的18:00 - 08:00以及周末的所有时间)。对两组的临床结局进行了比较。还评估了周末、夜间以及一周中不同日期收治对医院死亡率的影响。我们的结果显示,办公时间收治的患者与非办公时间收治的患者在ICU死亡率和医院死亡率方面无显著差异(分别为27.2%对27.4%,p = 1.000;38.9%对37.6%,p = 0.798)。两组的ICU住院时间、21天内无ICU时间以及住院时间也具有可比性。在392例需要机械通气的患者中,办公时间组和非办公时间组的呼吸机相关结局无显著差异。多因素逻辑回归分析表明,在我们的ICU中,周末、夜间或一周中任何一天收治的患者,调整后的医院死亡几率并无显著升高。总之,我们的结果表明,与办公时间收治相比,我们内科ICU的非办公时间收治与更差的ICU、医院和呼吸机相关结局无关。我们ICU的收治时间和日期与医院死亡率的显著差异也无关。

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