Huckfeldt Roger, Flick A Bart, Mikkelson Debbie, Lowe Cindy, Finley Phillip J
St. John's Regional Health Center, Springfield, Missouri 65804, USA.
J Burn Care Res. 2007 Sep-Oct;28(5):703-7. doi: 10.1097/BCR.0B013E318148C945.
Wound healing after graft closure of excised burn wounds is a critical factor in the recovery process after thermal injury. Processes that speed time to stable wound closure should lead to improved outcomes, shorter lengths of hospital stays, and decreased complications. A randomized clinical trial to test the ability of continuous direct anodal microcurrent application to silver nylon wound contact dressings was designed. Time for wound closure after split-thickness skin grafting was observed. Thirty patients with full-thickness thermal burns were randomized into two groups. The control group received postoperative dressing care using moistened silver nylon fabric covered with gauze after tangential burn wound excision and split-thickness skin grafting. The study group received an identical protocol with the addition of continuous direct anodal microcurrent application. Time to 95% wound closure was measured using digital photography. The digital photographs were evaluated by a burn surgeon blinded to the patient's randomization. An independent t-test was used to analyze the data. The study group experienced a 36% reduction in time to wound closure (mean of 4.6 days) as compared to the control group (mean of 7.2 days). This was statistically significant at a P value of <.05. The use of continuous direct anodal microcurrent decreased time to wound closure after split-thickness skin grafting.
切除烧伤创面植皮后的伤口愈合是热损伤后恢复过程中的一个关键因素。加快伤口稳定闭合时间的过程应能改善预后、缩短住院时间并减少并发症。设计了一项随机临床试验,以测试连续直接阳极微电流应用于银尼龙伤口接触敷料的能力。观察了削痂植皮后伤口闭合的时间。30例全层热烧伤患者被随机分为两组。对照组在削痂烧伤创面切除和削痂植皮后,使用覆盖有纱布的湿润银尼龙织物进行术后换药护理。研究组采用相同方案,并增加连续直接阳极微电流应用。使用数码摄影测量伤口闭合至95%的时间。数码照片由一位对患者随机分组不知情的烧伤外科医生进行评估。采用独立t检验分析数据。与对照组(平均7.2天)相比,研究组伤口闭合时间缩短了36%(平均4.6天)。在P值<0.05时,这具有统计学意义。连续直接阳极微电流的使用缩短了削痂植皮后伤口闭合的时间。