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本文引用的文献

1
Negative-pressure wound therapy II: negative-pressure wound therapy and increased perfusion. Just an illusion?负压伤口治疗II：负压伤口治疗与灌注增加。只是一种错觉？
Plast Reconstr Surg. 2009 Feb;123(2):601-612. doi: 10.1097/PRS.0b013e318196b97b.
2
A technique to visualize wound bed microcirculation and the acute effect of negative pressure.一种可视化伤口床微循环及负压急性效应的技术。
Wound Repair Regen. 2008 May-Jun;16(3):460-5. doi: 10.1111/j.1524-475X.2008.00390.x.
3
Integra in lower extremity reconstruction after burn injury.Integra用于烧伤后下肢重建。
Plast Reconstr Surg. 2008 Apr;121(4):1256-1262. doi: 10.1097/01.prs.0000304237.54236.66.
4
Vacuum-assisted closure for defects of the abdominal wall.腹壁缺损的负压封闭引流术。
Plast Reconstr Surg. 2008 Mar;121(3):832-839. doi: 10.1097/01.prs.0000299268.51008.47.
5
An improved alternative to vacuum-assisted closure (VAC) as a negative pressure dressing in lower limb split skin grafting: a clinical trial.一种在下肢分层皮片移植中作为负压敷料的改良型真空辅助闭合（VAC）替代方案：一项临床试验。
J Plast Reconstr Aesthet Surg. 2008;61(3):334-7. doi: 10.1016/j.bjps.2007.01.064. Epub 2007 Mar 9.
6
Vacuum assisted closure device improves the take of mesh grafts in chronic leg ulcer patients.负压封闭引流装置可提高慢性腿部溃疡患者网状移植物的成活率。
Dermatology. 2008;216(3):250-6. doi: 10.1159/000112937. Epub 2008 Jan 17.
7
Outcomes of skin graft reconstructions with the use of Vacuum Assisted Closure (VAC(R)) dressing for irradiated extremity sarcoma defects.使用负压封闭引流（VAC(R)）敷料修复放射性肢体肉瘤缺损的皮肤移植效果。
World J Surg Oncol. 2007 Nov 29;5:138. doi: 10.1186/1477-7819-5-138.
8
Use of the vacuum-assisted closure system in the treatment of enterocutaneous fistulas: a follow-up.真空辅助闭合系统在肠皮肤瘘治疗中的应用：随访研究
Plast Reconstr Surg. 2007 Sep 15;120(4):1092. doi: 10.1097/01.prs.0000278223.62852.ce.
9
Wound closure after split-thickness skin grafting is accelerated with the use of continuous direct anodal microcurrent applied to silver nylon wound contact dressings.在使用连续直接阳极微电流施加于银尼龙伤口接触敷料时，可加速分层皮片移植后的伤口闭合。
J Burn Care Res. 2007 Sep-Oct;28(5):703-7. doi: 10.1097/BCR.0B013E318148C945.
10
Securing skin grafts to microvascular free flaps using the vacuum-assisted closure (VAC) device.使用负压封闭引流（VAC）装置将皮肤移植物固定于游离微血管皮瓣。
Ann Plast Surg. 2007 May;58(5):573-6. doi: 10.1097/01.sap.0000237638.93453.66.

负压封闭引流技术可促进人工真皮在软组织缺损中的整合：Terudermis(®)和 Pelnac(®)。

Vacuum-assisted closure improves the incorporation of artificial dermis in soft tissue defects: Terudermis(®) and Pelnac(®).

机构信息

Department of Plastic and Reconstructive Surgery, DongGuk University International Hospital, Ilsan, South Korea.

出版信息

Int Wound J. 2011 Jun;8(3):261-7. doi: 10.1111/j.1742-481X.2011.00780.x. Epub 2011 Feb 25.

DOI:10.1111/j.1742-481X.2011.00780.x
PMID:21561535
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7950916/
Abstract

As a dermal scaffold, artificial dermal substitutes allow the body to accomplish its own tissue regeneration through infiltration of cells and neovascularisation. However, they show not only rather lower take rates compared to autologous skin grafts alone, but they also require more time for sufficient vascular ingrowth to overlay the skin graft. To accelerate this overlaying, we applied vacuum-assisted closure negative-pressure settings over the artificial dermis: Terudermis(®) and Pelnac(®) grafts. Fourteen patients with complex tissue defects were treated, including bone exposure in two cases, tendon exposure in seven cases and soft tissue defects in five cases. Nine cases had combined wound infections. The time interval between the first artificial dermis graft and the second split-thickness skin graft over it was 7·64 days on average. Dermal substitutes took place completely in all cases and there were no graft failures.

摘要

作为一种真皮支架，人工真皮替代品允许身体通过细胞浸润和新血管生成来完成自身组织再生。然而，与单独使用自体皮片相比，它们不仅具有较低的吸收率，而且还需要更多的时间来使足够的血管长入覆盖皮片。为了加速这种覆盖，我们在人工真皮上应用了负压封闭负压引流（VAC）装置：Terudermis(®)和 Pelnac(®)移植物。治疗了 14 例复杂组织缺损患者，其中包括 2 例骨外露、7 例肌腱外露和 5 例软组织缺损。9 例合并伤口感染。首次应用人工真皮与再次应用自体刃厚皮片之间的时间间隔平均为 7.64 天。所有病例的真皮替代物均完全替代，无移植物失败。