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球囊脉冲式血管内呼吸导管中血流的建模

Modeling of blood flow in a balloon-pulsed intravascular respiratory catheter.

作者信息

Zinovik Igor N, Federspiel William J

机构信息

Department of Chemical Engineering, Medical Devices Laboratory, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

出版信息

ASAIO J. 2007 Jul-Aug;53(4):464-8. doi: 10.1097/MAT.0b013e31805fe96d.

Abstract

A computational fluid dynamic (CFD) model was developed and used to simulate blood flow associated with our pulsating respiratory catheter. A principal goal of this CFD study was to evaluate how the balloon-generated flow permeated through the fiber bundle and interacted with the flow past the catheter. The simulation showed that the flow inside the fiber bundle was uniform longitudinally and circumferentially despite the nonuniform flow patterns around the bundle. Thus, the flow conditions inside the fiber bundle remained optimal for the blood oxygenation process. The results indicate the shunt flow around the fiber bundle decreased with increasing balloon pulsation rate.

摘要

开发了一种计算流体动力学(CFD)模型,并用于模拟与我们的脉动呼吸导管相关的血流。这项CFD研究的一个主要目标是评估球囊产生的血流如何渗透过纤维束,并与经过导管的血流相互作用。模拟结果表明,尽管纤维束周围的流动模式不均匀,但纤维束内部的血流在纵向和周向上都是均匀的。因此,纤维束内部的流动条件对于血液氧合过程仍然是最佳的。结果表明,随着球囊脉动率的增加,纤维束周围的分流减少。

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