Kucera Kristin A, Doss Amy E, Dunn Sarah S, Clemson Lindsey A, Zwischenberger Joseph B
Department of Surgery, University of Texas Medical Branch, Galveston, Texas 77555, USA.
ASAIO J. 2007 Jul-Aug;53(4):497-505. doi: 10.1097/MAT.0b013e3180616b5d.
In this review, we summarize the history of tracheal reconstruction and replacement as well as progress in current tracheal substitutes. In Part 1, we cover the historical highlights of grafts, flaps, tube construction, and tissue transplants and address the progress made in tracheal stenting as a means of temporary tracheal support. This is followed in Part 2 by an analysis of solid and porous tracheal prostheses in experimental and clinical trials. We conclude Part 2 with a summary of recent efforts toward generating a bioengineered trachea. Finally, we provide an algorithm on the spectrum of options available for tracheal replacement.
在本综述中,我们总结了气管重建与置换的历史以及当前气管替代物的进展。在第一部分,我们涵盖了移植物、皮瓣、人工气管构建和组织移植的历史亮点,并阐述了气管支架置入作为一种临时气管支撑手段所取得的进展。在第二部分,我们分析了实体和多孔气管假体在实验和临床试验中的情况。我们在第二部分结尾总结了近期在生物工程气管生成方面所做的努力。最后,我们提供了一个关于气管置换可用选项范围的算法。