Steger Volker, Hampel Martina, Trick Iris, Müller Michael, Walles Thorsten
Department of Thoracic Surgery, Klinik Schillerhoehe, Gerlingen, Germany.
Expert Rev Med Devices. 2008 Sep;5(5):605-12. doi: 10.1586/17434440.5.5.605.
The replacement of significant lengths of tracheal tissue still remains the unrivalled 'holy grail' of thoracic surgery. As a result of continuous developments and improvements in tracheal surgery throughout the last five decades, most tracheal lesions can now be resected and primary reconstruction effected safely. Today, very few patients present extensive tracheal lesions that necessitate tracheal replacement. The spectrum of tracheal substitutes ranges from autologous tissue flaps and patches to synthetic stents and prostheses to tissue-engineered scaffolding. In this review, the clinical achievements and conceivable developments of applying human allografts and biological and artificial prostheses will be discussed.
替换相当长一段气管组织仍然是胸外科无可匹敌的“圣杯”。在过去五十年里，气管外科不断发展和进步，如今大多数气管病变都能安全切除并进行一期重建。如今，需要进行气管置换的广泛气管病变患者已非常少见。气管替代物的范围从自体组织瓣和补片到合成支架及假体，再到组织工程支架。在这篇综述中，将讨论应用人类同种异体移植物以及生物和人工假体的临床成果及可能的发展。
