Poliakov V E
Pediatriia. 1991(11):103-9.
Short- and long-term results of combined treatment of 440 children and adolescents afflicted with lymphogranulomatosis (Hodgkin's disease) were traced. A group of 104 children received treatment in 1964-1973. Complete effect was attained in 72.1% of the patients (in 75 out of 104); the 5-year survival was 72.5%, the 10-year 61.1%, the 15-year 52.75%. The long-term results are described in detail. Analysis of the results allowed basing the necessity of the three-stage combined chemoradiation therapy in children with lymphogranulomatosis. In 1976-1980, the treatment according to the first combined program was provided to 193 children and adolescents aged 2.5 to 16 years suffering from lymphogranulomatosis. In 1979-1983, the treatment according to the second combined program was provided to 143 children and adolescents aged 3 to 15 years suffering from the same disease. In patients treated according to the first and second programs, the 5-year survival amounted to 81.3 and 93.3%, respectively. The total number of lethal outcomes was 20.2 and 4.2%, respectively, during the whole observation period.
对440名患有淋巴肉芽肿病（霍奇金病）的儿童和青少年进行联合治疗的短期和长期结果进行了追踪。1964年至1973年期间，一组104名儿童接受了治疗。72.1%的患者（104名中的75名）获得了完全缓解；5年生存率为72.5%，10年生存率为61.1%，15年生存率为52.75%。详细描述了长期结果。对结果的分析确定了对淋巴肉芽肿病患儿进行三阶段联合放化疗的必要性。1976年至1980年，按照第一个联合方案对193名年龄在2.5岁至16岁之间患有淋巴肉芽肿病的儿童和青少年进行了治疗。1979年至1983年，按照第二个联合方案对143名年龄在3岁至15岁之间患有同样疾病的儿童和青少年进行了治疗。按照第一个和第二个方案治疗的患者，5年生存率分别为81.3%和93.3%。在整个观察期内，致死率分别为20.2%和4.2%。
