Pangault Céline, Arlotto Marie, Berger François, De Vos John, Béné Marie-Christine, Fest Thierry
Département HITC, UPRES EA3889, CHU Pontchaillou, 35033 Rennes, France.
Med Sci (Paris). 2007 Mar;23 Spec No 1:13-7. doi: 10.1051/medsci/2007231s13.
Numerous parameters related to the patients and the conditions of the sample collection can affect the properties of a biological sample. The pre-analytical parameters are especially important to deal with in the setting of multicenter clinical trials. Here, we report the preliminary results of a trial conducted by the cooperative group GOELAMS (Groupe Ouest-Est des Leucémies aiguës et Autres Maladies du Sang) to define the pre-analytical parameters that affect the proteomic analysis of serum samples in patients with B-cell non Hodgkin lymphoma included in clinical trials.
许多与患者及样本采集条件相关的参数会影响生物样本的特性。在多中心临床试验中，分析前参数的处理尤为重要。在此，我们报告了由GOELAMS协作组（法国急性白血病和其他血液病东西方协作组）开展的一项试验的初步结果，该试验旨在确定影响临床试验中B细胞非霍奇金淋巴瘤患者血清样本蛋白质组分析的分析前参数。
