Matsumori Masamichi, Tanaka Hiroshi, Kawanishi Yujiro, Onishi Tetsuari, Nakagiri Keitaro, Yamashita Teruo, Okada Kenji, Okita Yutaka
Division of Cardiovascular, Thoracic, and Pediatric Surgery, Kobe University Graduate School of Medicine, 7-5-2, Kusunoki-cho, Chuo-ku, Kobe, 650-0017 Japan.
Interact Cardiovasc Thorac Surg. 2007 Apr;6(2):177-81. doi: 10.1510/icvts.2006.143289. Epub 2007 Jan 26.
The aim of this study is to evaluate distensibility of the aortic root and function of the aortic cusp after aortic root replacement using valve sparing procedure. Between October 1999 and August 2006, valve sparing aortic root replacements were performed in 39 patients who had annuloaortic ectasia (AAE) and aortic valve regurgitation. Reimplantation type of valve-sparing procedure was performed with a tube graft (n=12) or a Valsalva graft (n=27). Echocardiographic studies were performed six months after the operation comparing Valsalva graft (Group V, n=15), tube graft (Group T, n=5), and normal control (Group C, n=5). Percent changes in radius (PCR) of the aortic root were measured as indices of distensibility. Rapid valve opening velocity (RVOV/HR (mm/s/min)) and rapid valve closing velocity (RVCV/HR (mm/s/min)) of the aortic cusp were analyzed in each group. Root distensibility of sinus in Group T (1.9+/-1.1) was significantly smaller than Group C (7.2+/-1.8) (P=0.003). RVOV/HR in Group T was highest among the three groups (T: 48.2+/-6.2, V: 36.2+/-11.9, C: 33.7+/-9.6). RVCV/HR showed no difference among the three groups (T: 26.1+/-6.7, V: 40.7+/-16.6, C: 28.4+/-16.3). In conclusion, sinus distensibility of the Valsalva graft was well preserved and valve-opening characteristics with the Valsalva graft were identical to normal.
本研究的目的是评估采用保留瓣膜技术进行主动脉根部置换术后主动脉根部的扩张性及主动脉瓣叶的功能。1999年10月至2006年8月期间,对39例患有主动脉瓣环扩张(AAE)和主动脉瓣反流的患者进行了保留瓣膜的主动脉根部置换术。保留瓣膜手术的再植入类型采用人工血管(n = 12)或瓦氏窦人工血管(n = 27)进行。术后6个月进行超声心动图研究,比较瓦氏窦人工血管组(V组,n = 15)、人工血管组(T组,n = 5)和正常对照组(C组,n = 5)。测量主动脉根部半径的百分比变化(PCR)作为扩张性指标。分析每组主动脉瓣叶的快速瓣膜开放速度(RVOV/HR(mm/s/min))和快速瓣膜关闭速度(RVCV/HR(mm/s/min))。T组(1.9±1.1)的窦部扩张性明显小于C组(7.2±1.8)(P = 0.003)。T组的RVOV/HR在三组中最高(T组:48.2±6.2,V组:36.2±11.9,C组:33.7±9.6)。三组之间的RVCV/HR无差异(T组:26.1±6.7,V组:40.7±16.6,C组:28.4±16.3)。总之,瓦氏窦人工血管的窦部扩张性得到良好保留,且瓦氏窦人工血管的瓣膜开放特征与正常情况相同。