Singh Devender, Pinjala Rama Krishna, Reddy Rama Chandra, Satya Vani Pulitati Venkata Naga Laxmi
Department of Vascular Surgery and Endovascular Surgery, Nizam's Institute of Medical Sciences, Panjagutta, Hyderabad, Andhra Pradesh, 500082, India.
Interact Cardiovasc Thorac Surg. 2006 Dec;5(6):692-5. doi: 10.1510/icvts.2006.135772. Epub 2006 Aug 24.
The carotid body tumor is a rare neoplasm that has generated much literature over the last century, and for which continued controversy exists regarding natural history, biologic behavior, proper technique of excision, and the risk of morbidity and mortality. The present study reviewed a 16-year experience of managing carotid body paraganglioma (CBP) between 1988 and 2004. There were 10 consecutive patients aged between 18-42 years with tumors and median follow-up was 10 years. Preoperative information was derived from spiral CT scanning, magnetic resonance imaging (MRI), color Doppler imaging (CDI), and four-vessel digital subtraction arteriography. In five patients the tumor excision was attempted before they were referred to our tertiary care hospital. Two patients had bilateral tumors. Four patients had preoperative embolization, and blood loss was minimal, and excision was relatively easier in them. There was difficulty in deglutition (nasal and laryngeal regurgitation) in three patients with large tumors and who required nasogastric tube feeding (1 to 3 weeks). Surgical planning and prediction of peri-operative complications can be obtained by digital subtraction angiography, spiral CT angiography and color Doppler imaging. The peri-operative blood loss can be reduced by preoperative embolization.
颈动脉体瘤是一种罕见的肿瘤,在过去一个世纪里已有大量相关文献,然而对于其自然病史、生物学行为、恰当的切除技术以及发病和死亡风险仍存在持续的争议。本研究回顾了1988年至2004年间16年治疗颈动脉体副神经节瘤(CBP)的经验。连续有10例年龄在18至42岁之间的患者患有肿瘤,中位随访时间为10年。术前信息来自螺旋CT扫描、磁共振成像(MRI)、彩色多普勒成像(CDI)以及四血管数字减影血管造影。5例患者在转诊至我们的三级护理医院之前尝试过肿瘤切除。2例患者患有双侧肿瘤。4例患者进行了术前栓塞,失血极少,对他们而言切除相对更容易。3例患有大肿瘤且需要鼻饲管喂养(1至3周)的患者出现吞咽困难(鼻和喉反流)。通过数字减影血管造影、螺旋CT血管造影和彩色多普勒成像可进行手术规划和围手术期并发症预测。术前栓塞可减少围手术期失血。