Murray Elisabeth A, O'Doherty John P, Schoenbaum Geoffrey
Laboratory of Neuropsychology, National Institute of Mental Health, Bethesda, Maryland 20892, USA.
J Neurosci. 2007 Aug 1;27(31):8166-9. doi: 10.1523/JNEUROSCI.1556-07.2007.
When Pat Goldman-Rakic described the circuitry and function of primate prefrontal cortex in her influential 1987 monograph (Goldman-Rakic, 1987), she included only a few short paragraphs on the orbitofrontal cortex (OFC). That year, there were only nine papers published containing the term "orbitofrontal," an average of less than one paper per month. Twenty years later, this rate has increased to 32 papers per month. This explosive growth is partly attributable to the remarkable similarities that exist in structure and function across species. These similarities suggest that OFC function can be usefully modeled in nonhuman and even nonprimate species. Here, we review some of these similarities.
1987年，帕特·戈德曼-拉奇克在其颇具影响力的专著中描述了灵长类动物前额叶皮层的神经回路和功能（戈德曼-拉奇克，1987），其中关于眶额皮质（OFC）的内容仅有短短几段。当年，仅有9篇发表的论文包含“眶额”一词，平均每月不到1篇。20年后，这个数量增加到了每月32篇。这种爆炸式增长部分归因于不同物种在结构和功能上存在的显著相似性。这些相似性表明，OFC的功能可以在非人类甚至非灵长类物种中得到有效模拟。在此，我们回顾其中的一些相似之处。
