Lee Jong-Tae, Son Ji-Young, Kim Ho, Kim Sun-Young
Department of Public Health, Graduate School of Hanyang University, Hanyang University, Seoul, Korea.
Arch Environ Occup Health. 2006 May-Jun;61(3):123-30. doi: 10.3200/AEOH.61.3.123-130.
The authors evaluated whether the effects of air pollution on asthma in children differed by the regional socioeconomic status (SES) associated with the area in which children resided. They analyzed data on air pollution, asthma-related hospitalization, weather conditions, and SES collected from 25 subregions in Seoul from January 1 to December 31, 2002. The National Health Insurance Cooperation provided data for children aged younger than 15 years who were living in Seoul and hospitalized for asthma-related health conditions (ICD-10 codes J45-J46). Exposure to interquartile range increase of airborne particles < or = 10 microm in aerodynamic diameter, sulfur dioxide, and nitrogen dioxide in districts associated with a lower SES, the estimated percent increase of hospitalization for asthma among children was 31% (95% confidence interval [CI] = 14%-51%), 29% (95% CI = 8%-53%), and 29% (95% CI = 5%-58%), respectively. This suggests that not only biological sensitivity markers, but also the SES of subjects, should be considered as potentially confounding factors.
作者评估了空气污染对儿童哮喘的影响是否因与儿童居住地区相关的区域社会经济地位(SES)而异。他们分析了2002年1月1日至12月31日从首尔25个分区收集的空气污染、哮喘相关住院治疗、天气状况和社会经济地位的数据。国民健康保险合作社提供了居住在首尔且因哮喘相关健康状况住院(国际疾病分类第十版编码J45-J46)的15岁以下儿童的数据。在社会经济地位较低地区,空气中空气动力学直径小于或等于10微米的颗粒物、二氧化硫和二氧化氮的四分位距增加,儿童哮喘住院率估计分别增加31%(95%置信区间[CI]=14%-51%)、29%(95%CI=8%-53%)和29%(95%CI=5%-58%)。这表明,不仅生物敏感性标志物,而且受试者的社会经济地位,都应被视为潜在的混杂因素。