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韩国空气污染相关发病和死亡风险的研究现状

Current State of Research on the Risk of Morbidity and Mortality Associated with Air Pollution in Korea.

作者信息

Bae Sanghyuk, Kwon Ho Jang

机构信息

Department of Preventive Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Department of Preventive Medicine, Dankook University College of Medicine, Cheonan, Korea.

出版信息

Yonsei Med J. 2019 Mar;60(3):243-256. doi: 10.3349/ymj.2019.60.3.243.

Abstract

PURPOSE

The effects of air pollution on health can vary regionally. Our goal was to comprehensively review previous epidemiological studies on air pollution and health conducted in Korea to identify future areas of potential study.

MATERIALS AND METHODS

We systematically searched all published epidemiologic studies examining the association between air pollution and occurrence of death, diseases, or symptoms in Korea. After classifying health outcomes into mortality, morbidity, and health impact, we summarized the relationship between individual air pollutants and health outcomes.

RESULTS

We analyzed a total of 27 studies that provided 104 estimates of the quantitative association between risk of mortality and exposure to air pollutants, including particulate matter with aerodynamic diameter less than 10 μm, particulate matter with aerodynamic diameter less than 2.5 μm, sulfur dioxide, nitrogen dioxide, ozone, and carbon monoxide in Korea between January 1999 and July 2018. Regarding the association with morbidity, there were 38 studies, with 98 estimates, conducted during the same period. Most studies examined the short-term effects of air pollution using a time series or case-crossover study design; only three cohort studies that examined long-term effects were found. There were four health impact studies that calculated the attributable number of deaths or disability-adjusted life years due to air pollution.

CONCLUSION

There have been many epidemiologic studies in Korea regarding air pollution and health. However, the present review shows that additional studies, especially cohort and experimental studies, are needed to provide more robust and accurate evidence that can be used to promote evidence-based policymaking.

摘要

目的

空气污染对健康的影响可能因地区而异。我们的目标是全面回顾此前在韩国进行的关于空气污染与健康的流行病学研究,以确定未来潜在的研究领域。

材料与方法

我们系统检索了所有已发表的关于韩国空气污染与死亡、疾病或症状发生之间关联的流行病学研究。在将健康结果分为死亡率、发病率和健康影响后,我们总结了单个空气污染物与健康结果之间的关系。

结果

我们共分析了27项研究,这些研究提供了104项关于韩国1999年1月至2018年7月期间死亡率风险与空气污染物暴露之间定量关联的估计值,这些空气污染物包括空气动力学直径小于10μm的颗粒物、空气动力学直径小于2.5μm的颗粒物、二氧化硫、二氧化氮、臭氧和一氧化碳。关于与发病率的关联,同期有38项研究,提供了98项估计值。大多数研究采用时间序列或病例交叉研究设计来检验空气污染的短期影响;仅发现三项检验长期影响的队列研究。有四项健康影响研究计算了因空气污染导致的死亡归因数或伤残调整生命年。

结论

韩国已经有许多关于空气污染与健康的流行病学研究。然而,本次综述表明,需要更多的研究,尤其是队列研究和实验研究,以提供更有力和准确的证据,用于促进基于证据的政策制定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8ce/6391524/644a6592a725/ymj-60-243-g001.jpg

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