Mohanty Sambit K, Piccoli Anthony L, Devine Lisa J, Patel Ashokkumar A, William Gross C, Winters Sharon B, Becich Michael J, Parwani Anil V
Department of Biomedical Informatics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
BMC Cancer. 2007 Jul 31;7:144. doi: 10.1186/1471-2407-7-144.
Synoptic reporting, either as part of the pathology report or replacing some free text component incorporates standardized data elements in the form of checklists for pathology reporting. This ensures the pathologists make note of these findings in their reports, thereby improving the quality and uniformity of information in the pathology reports.
The purpose of this project is to develop the entire set of elements in the synoptic templates or "worksheets" for hematologic and lymphoid neoplasms using the World Health Organization (WHO) Classification and the College of American Pathologists (CAP) Cancer Checklists. The CAP checklists' content was supplemented with the most updated classification scheme (WHO classification), specimen details, staging as well as information on various ancillary techniques such as cytochemical studies, immunophenotyping, cytogenetics including Fluorescent In-situ Hybridization (FISH) studies and genotyping. We have used a digital synoptic reporting system as part of an existing laboratory information system (LIS), CoPathPlus, from Cerner DHT, Inc. The synoptic elements are presented as discrete data points, so that a data element such as tumor type is assigned from the synoptic value dictionary under the value of tumor type, allowing the user to search for just those cases that have that value point populated.
These synoptic worksheets are implemented for use in our LIS. The data is stored as discrete data elements appear as an accession summary within the final pathology report. In addition, the synoptic data can be exported to research databases for linking pathological details on banked tissues.
Synoptic reporting provides a structured method for entering the diagnostic as well as prognostic information for a particular pathology specimen or sample, thereby reducing transcription services and reducing specimen turnaround time. Furthermore, it provides accurate and consistent diagnostic information dictated by pathologists as a basis for appropriate therapeutic modalities. Using synoptic reports, consistent data elements with minimized typographical and transcription errors can be generated and placed in the LIS relational database, enabling quicker access to desired information and improved communication for appropriate cancer management. The templates will also eventually serve as a conduit for capturing and storing data in the virtual biorepository for translational research. Such uniformity of data lends itself to subsequent ease of data viewing and extraction, as demonstrated by rapid production of standardized, high-quality data from the hemopoietic and lymphoid neoplasm specimens.
概要报告作为病理报告的一部分或取代某些自由文本部分,以病理报告清单的形式纳入标准化数据元素。这确保病理学家在其报告中记录这些发现,从而提高病理报告中信息的质量和一致性。
本项目的目的是利用世界卫生组织(WHO)分类和美国病理学家学会(CAP)癌症清单,开发血液和淋巴肿瘤概要模板或“工作表”中的整套元素。CAP清单的内容通过最新的分类方案(WHO分类)、标本细节、分期以及各种辅助技术的信息(如细胞化学研究、免疫表型分析、包括荧光原位杂交(FISH)研究的细胞遗传学和基因分型)进行补充。我们使用了数字概要报告系统,作为来自Cerner DHT公司的现有实验室信息系统(LIS)CoPathPlus的一部分。概要元素以离散数据点的形式呈现,这样诸如肿瘤类型等数据元素从肿瘤类型值下的概要值字典中分配,允许用户仅搜索那些填充了该值点的病例。
这些概要工作表已在我们的LIS中实施使用。数据作为离散数据元素存储,在最终病理报告中显示为一份送检摘要。此外,概要数据可导出到研究数据库,用于链接存档组织的病理细节。
概要报告为输入特定病理标本或样本的诊断及预后信息提供了一种结构化方法,从而减少转录工作并缩短标本周转时间。此外,它提供了由病理学家规定的准确且一致的诊断信息,作为适当治疗方式的基础。使用概要报告,可以生成具有最小排版和转录错误的一致数据元素,并将其放置在LIS关系数据库中,从而能够更快地获取所需信息,并改善癌症管理的沟通。这些模板最终还将作为在虚拟生物样本库中捕获和存储数据以进行转化研究的渠道。数据的这种一致性便于后续的数据查看和提取,从造血和淋巴肿瘤标本快速生成标准化、高质量的数据就证明了这一点。