Donahoe D H, Meador M, Fortune T, Llorena R
W V Med J. 1991 Oct;87(10):468-70.
Clomipramine hydrochloride, a tricyclic antidepressant that blocks serotonin and norepinephrine reuptake, is indicated in the treatment of Obsessive-Compulsive Disorder. It has been reported that patients with Obsessive-Compulsive Disorder and a concomitant diagnosis of Tourette's Syndrome respond well to treatment with clomipramine (1). It has also been reported that these dually-diagnosed patients, when treated with clomipramine, receive relief from the symptoms of both disorders (2). Published reports of Tourette's patients, without a concomitant Obsessive-Compulsive Disorder, successfully responding to treatment with clomipramine are rare. To the authors' knowledge, no such report has been published since 1975. This article reports the case of a 41-year-old male Tourette's patient, without a dual diagnosis of Obsessive-Compulsive Disorder, who successfully responded to clomipramine therapy.
盐酸氯米帕明是一种三环类抗抑郁药，可阻断5-羟色胺和去甲肾上腺素的再摄取，用于治疗强迫症。据报道，患有强迫症并同时诊断为妥瑞氏综合征的患者对氯米帕明治疗反应良好（1）。也有报道称，这些双重诊断的患者在接受氯米帕明治疗后，两种疾病的症状都得到了缓解（2）。关于没有合并强迫症的妥瑞氏症患者成功接受氯米帕明治疗的公开报道很少。据作者所知，自1975年以来尚未发表过此类报告。本文报告了一例41岁男性妥瑞氏症患者，未合并强迫症诊断，成功接受氯米帕明治疗的病例。
