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Does triple-negative phenotype accurately identify basal-like tumour? An immunohistochemical analysis based on 143 'triple-negative' breast cancers.

作者信息

Bidard F-C, Conforti R, Boulet T, Michiels S, Delaloge S, André F

出版信息

Ann Oncol. 2007 Jul;18(7):1285-6. doi: 10.1093/annonc/mdm360.

DOI:10.1093/annonc/mdm360
PMID:17675400
Abstract
摘要

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Does triple-negative phenotype accurately identify basal-like tumour? An immunohistochemical analysis based on 143 'triple-negative' breast cancers.三阴性表型能否准确识别基底样肿瘤?基于143例“三阴性”乳腺癌的免疫组织化学分析。
Ann Oncol. 2007 Jul;18(7):1285-6. doi: 10.1093/annonc/mdm360.
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Basal cytokeratin and epidermal growth factor receptor expression are not predictive of BRCA1 mutation status in women with triple-negative breast cancers.基底细胞角蛋白和表皮生长因子受体的表达与三阴性乳腺癌女性的 BRCA1 突变状态无关。
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Basal-HER2 phenotype shows poorer survival than basal-like phenotype in hormone receptor-negative invasive breast cancers.在激素受体阴性浸润性乳腺癌中,基底-HER2表型的生存率低于基底样表型。
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Triple-negative and HER2-overexpressing breast cancers exhibit an elevated risk and an earlier occurrence of cerebral metastases.三阴性和 HER2 过表达型乳腺癌具有更高的颅内转移风险和更早的发生。
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Eur J Cancer. 2009 Sep;45 Suppl 1:5-10. doi: 10.1016/S0959-8049(09)70011-5.

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