Pincus Theodore, Yazici Yusuf, Bergman Martin, Maclean Ross, Harrington Timothy
NYU Hospital for Joint Diseases, 301 East 17 Street, New York, NY 10003, USA.
Best Pract Res Clin Rheumatol. 2007 Aug;21(4):789-804. doi: 10.1016/j.berh.2007.02.009.
A continuous quality improvement approach is proposed for the assessment and management of patients with rheumatoid arthritis (RA) based on scores on a one-page patient self-report multidimensional health assessment questionnaire (MDHAQ), without formal joint counts. The approach includes five simple steps before the patient is seen by the physician: (1) an MDHAQ is completed by every patient at every visit; (2) scores are calculated for patient function, pain, and global estimate, with options for a self-report joint count and other scales; (3) scores are entered on flow sheets with data from prior visits, which might also include laboratory and medication information; (4) scores are compiled into an index termed Routine Assessment of Patient Index Data (RAPID), analogous to a Disease Activity Score (DAS); (5) RAPID scores are classified to guide treatment decisions. RAPID 3 includes the three patient-reported outcome (PRO) measures in the RA Core Data Set - physical function, pain, and global estimate. RAPID 4 adds a self-report joint count, and RAPID 5, a physician global estimate. RAPID 3 can be calculated in about 10 seconds, RAPID 4 in about 19 seconds, and RAPID 5 in about 20 seconds. RAPID 3, RAPID 4, and RAPID 5 give similar results to distinguish active from control treatments in RA clinical trials, at levels similar to American College of Rheumatology or DAS improvement criteria, and are all correlated significantly with DAS28 (rho=0.62-0.64, P<0.001). A proposed classification of RAPID scores, analogous to four DAS28 categories, includes: 'near remission' (0-1), 'low severity' (1.01-2), 'moderate severity' (2.01-4), and 'high severity' (>4). RAPID scoring is feasible in standard clinical care to support continuous quality improvement.
本文提出了一种基于单页患者自我报告多维健康评估问卷(MDHAQ)评分的类风湿关节炎(RA)患者评估与管理的持续质量改进方法,无需进行正式的关节计数。该方法在患者就诊前包括五个简单步骤:(1)每位患者每次就诊时均需完成MDHAQ;(2)计算患者功能、疼痛及整体评估得分,并可选择自我报告关节计数及其他量表;(3)将得分与之前就诊的数据录入流程图,这些数据可能还包括实验室及用药信息;(4)将得分汇总成一个名为患者指标数据常规评估(RAPID)的指数,类似于疾病活动评分(DAS);(5)对RAPID得分进行分类以指导治疗决策。RAPID 3包括RA核心数据集中的三项患者报告结局(PRO)指标——身体功能、疼痛及整体评估。RAPID 4增加了自我报告关节计数,RAPID 5增加了医生整体评估。RAPID 3约10秒即可算出,RAPID 4约19秒,RAPID 5约20秒。在RA临床试验中,RAPID 3、RAPID 4和RAPID 5区分活性治疗与对照治疗的结果相似,与美国风湿病学会或DAS改善标准相当,且均与DAS28显著相关(rho=0.62 - 0.64,P<0.001)。一种类似于DAS28四类的RAPID得分分类建议包括:“接近缓解”(0 - 1)、“低严重度”(1.01 - 2)、“中度严重度”(2.01 - 4)及“高严重度”(>4)。RAPID评分在标准临床护理中可行,有助于持续质量改进。