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女童生殖道横纹肌肉瘤的近距离放射治疗:技术要点、报告及展望。

Brachytherapy for genital-tract rhabdomyosarcomas in girls: technical aspects, reports, and perspectives.

作者信息

Magné Nicolas, Haie-Meder Christine

机构信息

Department of Radiotherapy, Brachytherapy Service, Institute Gustave Roussy, Villejuif, France.

出版信息

Lancet Oncol. 2007 Aug;8(8):725-9. doi: 10.1016/S1470-2045(07)70240-1.

Abstract

Rhabdomyosarcoma is a mesenchymal disease that represents 15-20% of childhood cancers and is the most common soft-tissue tumour in children. Most reviews on paediatric brachytherapy have described the experience of expert institutions with different brachytherapy techniques in a heterogeneous set of childhood malignant diseases. Brachytherapy reports focusing on specific types or locations (or both) are scarce. Rhabdomyosarcoma of the genital tract is recognised as one of the most curable forms of rhabdomyosarcoma. A multidisciplinary approach with more efficacious multidrug chemotherapy, conservative surgery, and limited radiotherapy, such as brachytherapy, has been used to help improve success rates. This review aims to offer perspectives and analysis on the effectiveness and complications of brachytherapy in gynaecological rhabdomyosarcoma management.

摘要

横纹肌肉瘤是一种间叶组织疾病,占儿童癌症的15%-20%,是儿童最常见的软组织肿瘤。大多数关于儿童近距离放射治疗的综述描述了专家机构在一组异质性儿童恶性疾病中采用不同近距离放射治疗技术的经验。专注于特定类型或部位(或两者)的近距离放射治疗报告很少。生殖道横纹肌肉瘤被认为是横纹肌肉瘤最可治愈的形式之一。一种多学科方法,包括更有效的多药化疗、保守手术和有限的放射治疗,如近距离放射治疗,已被用于帮助提高成功率。本综述旨在对近距离放射治疗在妇科横纹肌肉瘤治疗中的有效性和并发症提供观点和分析。

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