Kushch N L, Iulish E I, Prikhodchenko V V, Agaev A A, Kushch N N
Anesteziol Reanimatol. 1991 Sep-Oct(5):15-7.
Clinical and immunological studies of 65 patients with extremely severe disseminated suppurative peritonitis have revealed profound disturbances in their immune status. A considerable (2.5-3-fold) decrease in phagocytosis and complement activity, a drastic drop in T-, B-lymphocyte and T-helper content and a depression in T-lymphocyte functional activity have been observed. All this was accompanied by the activation of allergic and autoimmune reactions. Single transfusion of extracorporally X-ray-irradiated autoblood (5-7% of circulating blood volume) promoted an earlier normalization of the patients' critical condition and a prompt correction of the immune shifts.
对65例极重度弥漫性化脓性腹膜炎患者的临床和免疫学研究显示，他们的免疫状态存在严重紊乱。观察到吞噬作用和补体活性显著（2.5至3倍）降低，T淋巴细胞、B淋巴细胞和辅助性T细胞数量急剧下降，T淋巴细胞功能活性受到抑制。所有这些都伴随着过敏和自身免疫反应的激活。单次输注经体外X射线照射的自体血（占循环血量的5 - 7%）促进了患者危急状况的更早正常化以及免疫变化的迅速纠正。
