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[置换-替代血浆置换术后重症化脓性败血症患儿免疫指标的动态变化]

[Dynamics of immunologic indicators in children with severe forms of suppurative-septic diseases after the exchange-substitute plasmapheresis].

作者信息

Shabalin V N, Davatdarova G M, Duriagin D S, Kreslavskaia E E, Tsuman V G, Ol'shanskaia A Ia

出版信息

Sov Med. 1991(1):19-21.

PMID:1862373
Abstract

Time course of the immunity system parameters was followed in children suffering from grave endotoxicosis forms treated by discrete plasmapheresis (DPA) as the emergency therapeutic measure. T, T-active, B lymphocytes, O cells, immunoglobulins A, G, M were analyzed, as were the counts of phagocytizing leukocytes and circulating immune complexes. The infectious process was found to lead to a temporary relative secondary immunodeficiency. DPA with perfusion of hyperimmune plasma resulted in rapid correction of all component of the immunity system, paralleled by normalization of the general clinical status of the patients, and prevented chronic transformation of the process.

摘要

对采用间断性血浆置换术(DPA)作为紧急治疗措施治疗的重症内毒素血症患儿的免疫系统参数随时间的变化情况进行了跟踪。分析了T细胞、T活性细胞、B淋巴细胞、O细胞、免疫球蛋白A、G、M,以及吞噬白细胞计数和循环免疫复合物。发现感染过程会导致暂时性相对继发性免疫缺陷。输注超免疫血浆的DPA导致免疫系统所有成分迅速得到纠正,同时患者的一般临床状况恢复正常,并防止了该过程的慢性转变。

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