Shanin Iu N, Shanin V Iu
Anesteziol Reanimatol. 1991 Sep-Oct(5):24-7.
The impact of different variants of neuroleptanalgesia (NLA) on respiration immediately after gastric resection and cholecystectomy has been studied in two homogeneous groups of patients (30 persons each) after operations on the upper abdominal organs. In patients of group I NLA was performed using fentanyl (initial dose--7.5 micrograms/kg, maintenance dose--100 micrograms) supplemented with epidural blockade and isovolemic hemodilution. In patients of group II NLA was performed with graded administration of 100-200 micrograms fentanyl. In patients of group I right after surgery gas exchange during room air inhalation was unimpaired, while in patients of group II hypoxemia due to inadequate ventilation and metabolic acidosis were registered. It is concluded that the type of anesthesia management suggested has a protective effect on respiration in the earliest postoperative period.
在两组各30例接受上腹部器官手术的患者中,研究了不同类型的神经安定镇痛(NLA)对胃切除和胆囊切除术后即刻呼吸的影响。第一组患者采用芬太尼进行NLA(初始剂量——7.5微克/千克,维持剂量——100微克),并辅以硬膜外阻滞和等容血液稀释。第二组患者采用分次给予100 - 200微克芬太尼进行NLA。第一组患者术后即刻吸入室内空气时气体交换未受影响,而第二组患者出现了因通气不足导致的低氧血症和代谢性酸中毒。结论是,所建议的麻醉管理方式对术后早期呼吸具有保护作用。