Brotto Lori A, Heiman Julia R, Goff Barbara, Greer Benjamin, Lentz Gretchen M, Swisher Elizabeth, Tamimi Hisham, Van Blaricom Amy
Department of Obstetrics and Gynaecology, University of British Columbia, 2775 Laurel Street, Vancouver, BC, Canada V5Z 1M9,
Arch Sex Behav. 2008 Apr;37(2):317-29. doi: 10.1007/s10508-007-9196-x. Epub 2007 Aug 7.
Treatment of early-stage cervical and endometrial cancer has been associated with significant sexual difficulties in at least half of women following hysterectomy. Despite the fact that women report such sexual side effects to be the most distressing aspect of their cancer treatment, evidence-based treatments for Female Sexual Arousal Disorder (FSAD), the most common sexual symptom in this group, do not exist. We developed and pilot tested a brief, three session psychoeducational intervention (PED) targeting FSAD in 22 women with early-stage gynecologic cancer. The PED consisted of three, 1-h sessions that combined elements of cognitive and behavioral therapy with education and mindfulness training. Women completed questionnaires and had a physiological measurement of genital arousal at pre- and post-PED (sessions 1 and 4) and participated in a semi-structured interview (session 4) during which their feedback on the PED was elicited. There was a significant positive effect of the PED on sexual desire, arousal, orgasm, satisfaction, sexual distress, depression, and overall well-being, and a trend towards significantly improved physiological genital arousal and perceived genital arousal. Qualitative feedback indicated that the PED materials were very user-friendly, clear, and helpful. In particular, women reported the mindfulness component to be most helpful. These findings suggest that a brief 3-session PED can significantly improve aspects of sexual response, mood, and quality of life in gynecologic cancer patients, and has implications for establishing the components of a psychological treatment program for FSAD.
早期宫颈癌和子宫内膜癌的治疗与至少半数女性子宫切除术后出现的严重性功能障碍有关。尽管女性报告称这些性副作用是她们癌症治疗中最令人痛苦的方面,但针对女性性唤起障碍(FSAD,该群体中最常见的性症状)的循证治疗方法并不存在。我们针对22名早期妇科癌症女性患者的FSAD开发并进行了一项简短的、共三节课的心理教育干预(PED)试点测试。PED包括三节课,每节1小时,将认知和行为疗法的元素与教育及正念训练相结合。女性在PED前(第1节)和后(第4节)完成问卷调查并进行生殖器唤起的生理测量,并在第4节参与半结构化访谈,期间收集她们对PED的反馈。PED对性欲、唤起、性高潮、满意度、性困扰、抑郁和总体幸福感有显著的积极影响,并且在生理生殖器唤起和感知到的生殖器唤起方面有显著改善的趋势。定性反馈表明,PED材料非常便于使用、清晰且有帮助。尤其是,女性报告称正念部分最有帮助。这些发现表明,一个简短的三节课PED可以显著改善妇科癌症患者的性反应、情绪和生活质量方面,并对确定FSAD心理治疗方案的组成部分有启示意义。