Leiblum Sandra, Seehuus Martin, Goldmeier David, Brown Candace
UNDNJ-Robert Wood Johnson Medical School-Psychiatry, Piscataway, NJ 08854, USA.
J Sex Med. 2007 Sep;4(5):1358-66. doi: 10.1111/j.1743-6109.2007.00575.x. Epub 2007 Aug 2.
Little is known about the etiology or medical/psychological correlates of persistent genital arousal disorder (PGAD).
The aims of this article were (i) to replicate the findings of earlier research identifying two subtypes of women with persistent arousal-those who meet all features of the condition and are at least moderately distressed, and those who meet only some features and are less distressed; and (ii) to identify the medical, psychological and/or pharmacological correlates of the condition.
A comprehensive web-based survey of persistent genital arousal (PGA) was posted on several Internet websites. Of the 156 women who completed the survey, 76 met all five features qualifying for a persistent genital arousal disorder (PGAD) group, and 48 met only some features (non-PGAD group).
The main outcome measures were endorsement of diagnostic signs of depression, anxiety, obsessive-compulsive disorder, and panic attack as well as medical illnesses and pharmacological preparations.
Compared to non-PGA subjects, women with PGA were significantly more likely to be depressed (55% vs. 38%) and to report panic attacks (31.6% vs. 14.6%). They were more anxious and more likely to monitor their physical sensations. Both groups reported high rates of childhood and adult sexual abuse, although the PGA women reported a higher prevalence of sexual victimization. They were significantly more likely to endorse negative feelings about their genital sensations and also more likely to complain of chronic fatigue syndrome than women without the condition (10% vs. 0%). There were no significant relationships with pharmacologic agents and symptoms.
Women who met all the criteria of PGAD were more likely than women who only met some of the criteria to report depression, anxiety, panic attacks, and certain obsessive-compulsive symptoms such as monitoring their physical sensations. It is hypothesized that for a subset of women, psychological factors, namely anxiety, reinforce exacerbate and maintain PGAD.
对于持续性性唤起障碍（PGAD）的病因或医学/心理关联知之甚少。
本文的目的是（i）重复早期研究的结果，确定持续性性唤起的两种女性亚型——符合该病症所有特征且至少中度痛苦的女性，以及仅符合部分特征且痛苦程度较轻的女性；（ii）确定该病症的医学、心理和/或药理学关联。
在多个互联网网站上发布了一项关于持续性性唤起（PGA）的全面网络调查。在完成调查的156名女性中，76名符合持续性性唤起障碍（PGAD）组的所有五项特征，48名仅符合部分特征（非PGAD组）。
主要观察指标是对抑郁、焦虑、强迫症和惊恐发作的诊断体征以及医学疾病和药物制剂的认可。
与非PGA受试者相比，患有PGA的女性明显更易患抑郁症（55%对38%）并报告有惊恐发作（31.6%对14.6%）。她们更焦虑，更倾向于关注自己的身体感觉。两组报告的童年和成年期性虐待发生率都很高，尽管患有PGA的女性报告的性受害患病率更高。与没有该病症的女性相比，她们明显更可能认可对自己性感觉的负面情绪，也更可能抱怨慢性疲劳综合征（10%对0%）。与药物制剂和症状没有显著关系。
符合PGAD所有标准的女性比仅符合部分标准的女性更有可能报告抑郁、焦虑、惊恐发作以及某些强迫症状，如关注自己的身体感觉。据推测，对于一部分女性来说，心理因素，即焦虑，会加剧并维持PGAD。
