植物油菜素类固醇信号传导中的14-3-3蛋白

14-3-3 proteins in plant brassinosteroid signaling.

作者信息

de Vries Sacco C

机构信息

Laboratory of Biochemistry, Department of Food Sciences and Nutrition, Wageningen University, Dreijenlaan 3, 6703 HA Wageningen, The Netherlands.

出版信息

Dev Cell. 2007 Aug;13(2):162-4. doi: 10.1016/j.devcel.2007.07.009.

DOI:10.1016/j.devcel.2007.07.009

PMID:17681126

Abstract

Brassinosteroid (BR) signaling requires the BIN2 kinase-promoted interaction of 14-3-3 proteins with the transcriptional regulators BZR1 and BZR2, which are subsequently redistributed to the cytoplasm by BRs. In this issue of Developmental Cell, Gampala et al. show that this redistribution may fine-tune BR responses and serve to crosstalk with other signaling pathways.

摘要

油菜素类固醇（BR）信号传导需要BIN2激酶促进14-3-3蛋白与转录调节因子BZR1和BZR2相互作用，随后这些转录调节因子会被BR重新分配到细胞质中。在本期《发育细胞》中，甘帕拉等人表明，这种重新分配可能会微调BR反应，并与其他信号通路产生串扰。