Brocks V, Bang J
Department of Obstetrics and Gynecology, Rigshospitalet, University of Copenhagen, Denmark.
Fetal Diagn Ther. 1991;6(1-2):37-45. doi: 10.1159/000263623.
A low risk population was offered screening for malformations in the second and third trimesters of pregnancy. Of 16,763 scans of pregnancies in the second trimester, 61 malformations were identified (0.36%). In the third trimester, scanning of 10,752 pregnancies revealed 24 malformations (0.22%): in all, in a low risk population 0.58% major malformations were found. The sensitivity for noncardiac malformations of the second trimester scanning was 54.3 with a specificity of 99.9%. The malformations overlooked was a more benign spectrum than the cases diagnosed. The sensitivity for cardiac malformations was less than 20%.
