Motegi Sei-ichiro, Tamura Atsushi, Okada Etsuko, Nagai Yayoi, Ishikawa Osamu
Department of Dermatology, Gunma University Graduate School of Medicine, Gunma, Japan.
Dermatology. 2007;215(2):147-51. doi: 10.1159/000104267.
The treatment of severe lymphedema is a difficult challenge. We performed lymphaticovenular anastomosis on two patients with secondary skin lesions of chronic lymphedema; one patient exhibited acquired lymphangioma circumscriptum of the vulva and the other presented elephantiasis nostras verrucosa of the lower leg. Both patients obtained a remarkable improvement in skin lesions and also in the reduction of lymphedema of the lower extremity. During a 6-month-follow-up period, constant reduction in the circumference of the lower extremities without exacerbation of skin lesions was achieved in both patients. Lymphaticovenular anastomosis is a useful surgical treatment for secondary lymphedema in the lower extremities. In addition, this surgical treatment is effective for secondary lesions of lymphedema, including acquired lymphangioma circumscriptum and elephantiasis nostras verrucosa.
重度淋巴水肿的治疗是一项艰巨的挑战。我们对两名患有慢性淋巴水肿继发性皮肤病变的患者进行了淋巴管静脉吻合术;一名患者表现为外阴部后天性局限性淋巴管瘤,另一名患者表现为小腿部疣状象皮病。两名患者的皮肤病变均有显著改善,下肢淋巴水肿也有所减轻。在6个月的随访期内,两名患者下肢周长持续减小,且皮肤病变未加重。淋巴管静脉吻合术是治疗下肢继发性淋巴水肿的一种有效手术方法。此外,这种手术治疗对淋巴水肿的继发性病变有效,包括后天性局限性淋巴管瘤和疣状象皮病。