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[获得性免疫缺陷综合征中小脑微血管的变化]

[Changes in the small cerebral vessels in the acquired immunodeficiency syndrome].

作者信息

Ferrer X, Aguilar M, Arbizu T, Podzamcer D, Bolao F, Martos A, Peres Serra J

机构信息

Servicio de Neurología, Universitat de Barcelona.

出版信息

Neurologia. 1991 Aug-Sep;6(7):238-41.

PMID:1768441
Abstract

In the necropsy exam of the brains of 13 patients with acquired immune deficiency syndrome (AIDS) cerebrovascular lesions were seen in 5 cases, three of them having AIDS encephalopathy. Hyalinosis was noted in 3 cases, and endarteritis obliterans and fibrinoid necrosis in one case each; both of them had associated perivascular lymphocytic infiltrates. Cerebral infarction was observed in one case, but no hemorrhages were seen. The neuropathological anomalies in four children affected with the AIDS are reported too, being an extensive calcified vasculopathy and changes suggesting active AIDS encephalopathy the main findings.

摘要

在对13例获得性免疫缺陷综合征(AIDS)患者的脑部进行尸检时,5例发现脑血管病变,其中3例患有AIDS脑病。3例出现玻璃样变性,1例分别出现闭塞性动脉内膜炎和纤维蛋白样坏死;二者均伴有血管周围淋巴细胞浸润。1例观察到脑梗死,但未见出血。还报告了4例患AIDS儿童的神经病理学异常,主要发现为广泛的钙化性血管病变和提示活动性AIDS脑病的改变。

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