主动吸烟和被动吸烟在墨西哥城肺癌病因学中的作用。

Role of active and passive smoking on lung cancer etiology in Mexico City.

作者信息

Franco-Marina Francisco, Villalba Caloca Jaime, Corcho-Berdugo Alexander

机构信息

Centro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, México.

出版信息

Salud Publica Mex. 2006;48 Suppl 1:S75-82. doi: 10.1590/s0036-36342006000700009.

DOI:10.1590/s0036-36342006000700009

PMID:17684692

Abstract

OBJECTIVE

[corrected] To estimate the association between passive and active smoking exposures and lung cancer in Mexico City and the corresponding attributable risks.

MATERIAL AND METHODS

Data was analyzed from a multicenter population-based case-control study conducted in Mexico City.

RESULTS

ORs for lung cancer in ever smokers were 6.2 (95% CI 3.9-10.2) for males and 2.8 (95% CI 1.7-4.4) for females. Passive smoking at home showed an overall OR of 1.8 (95% CI 1.3-2.6), similar in both genders. Attributable risk for active smoking for both genders combined, and for males and females separately, was estimated at 55, 76 and 27%, respectively. Attributable risk for passive smoking at home was 17% for females, 3.9% for males and 12% for the entire population.

CONCLUSIONS

In Mexico City smoking is attributable to a smaller proportion of lung cancer cases than in developed countries. This is explained by a lower intensity of smoking in the Mexican population.

摘要

目的

[已校正]评估墨西哥城被动吸烟和主动吸烟暴露与肺癌之间的关联以及相应的归因风险。

材料与方法

分析了在墨西哥城开展的一项基于多中心人群的病例对照研究的数据。

结果

曾经吸烟者患肺癌的比值比，男性为6.2（95%可信区间3.9 - 10.2），女性为2.8（95%可信区间1.7 - 4.4）。在家中被动吸烟的总体比值比为1.8（95%可信区间1.3 - 2.6），男女相似。男女合并、男性和女性单独的主动吸烟归因风险估计分别为55%、76%和27%。在家中被动吸烟的归因风险，女性为17%，男性为3.9%，总体人群为12%。