Smith James L, Bayles Darrell
Microbial Food Safety Research Unit, Eastern Regional Research Center, Agricultural Research Service, US Department of Agriculture, 600 East Mermaid Lane, Wyndmoor, Pennsylvania 19038, USA.
J Food Prot. 2007 Jul;70(7):1762-9. doi: 10.4315/0362-028x-70.7.1762.
Irritable bowel syndrome (IBS) is a commonly diagnosed disease characterized by gastrointestinal symptoms that may be associated with psychological illness and emotional problems. The prevalence rate worldwide for IBS ranges from 10 to 20% and is higher for women than for men. IBS imposes a substantial financial burden on both patients and employers because of increased medical costs and decreased work productivity. Recent studies indicate that inflammatory processes involving the gastrointestinal tract are strongly correlated with IBS. Acute bacterial gastroenteritis has been linked with the onset of symptoms in approximately 15% of patients diagnosed with IBS; these cases have been called postinfectious IBS. Organisms commonly associated with postinfectious IBS include the foodborne pathogens Campylobacter, Escherichia coli, Salmonella, and Shigella. The pathologic changes associated with postinfectious IBS are likely due to inflammatory reactions induced by the infecting organisms. Postinfectious IBS should be recognized as a potential long-term consequence of foodborne gastroenteritis.
肠易激综合征（IBS）是一种常见的诊断疾病，其特征为胃肠道症状，可能与心理疾病和情绪问题有关。IBS在全球的患病率为10%至20%，女性患病率高于男性。由于医疗费用增加和工作效率下降，IBS给患者和雇主都带来了巨大的经济负担。最近的研究表明，涉及胃肠道的炎症过程与IBS密切相关。急性细菌性肠胃炎与约15%被诊断为IBS的患者的症状发作有关；这些病例被称为感染后IBS。与感染后IBS常见相关的病原体包括食源性病原体弯曲杆菌、大肠杆菌、沙门氏菌和志贺氏菌。与感染后IBS相关的病理变化可能是由感染病原体引起的炎症反应所致。感染后IBS应被视为食源性肠胃炎的潜在长期后果。
