Porsgaard Trine, Overgaard Julie, Krogh Anne Louise, Jensen Mette Behrmann, Guo Zheng, Mu Huiling
BioCentrum-DTU, Technical University of Denmark, 2800 Lyngby, Denmark.
J Agric Food Chem. 2007 Sep 5;55(18):7615-9. doi: 10.1021/jf071389d. Epub 2007 Aug 8.
Many studies have shown beneficial effects of long chain n-3 polyunsaturated fatty acids (PUFA) on human health. Regardless of the positive effects of n-3 PUFA, the intake of these fatty acids remains low. An approach to increase the intake of n-3 PUFA in the population is to incorporate fish oil into food. In the present study, fish oil was incorporated into butter blends by enzymatic interesterification. The aim of the study was to investigate the effects of this butter product in comparison with a commercial butter blend and a product produced by interesterification but without fish oil. Golden Syrian hamsters received hamster feed blended with one of the three butter products. After 6 weeks of feeding, the fatty acid compositions of plasma, erythrocytes, liver, brain, and visceral fat were determined. The intake of butter product with fish oil resulted in a higher level of n-3 PUFA in plasma, erythrocytes, and liver. The incorporation of n-3 PUFA was significantly higher in phospholipids than in triacylglycerols. The results suggest that enriching butter blends with small amounts of fish oil can be used as an alternative method for improving the level of n-3 PUFA in biological tissues.
许多研究表明，长链n-3多不饱和脂肪酸（PUFA）对人体健康有益。尽管n-3 PUFA有积极作用，但这些脂肪酸的摄入量仍然很低。增加人群中n-3 PUFA摄入量的一种方法是将鱼油添加到食物中。在本研究中，通过酶促酯交换反应将鱼油添加到混合黄油中。本研究的目的是将这种黄油产品与市售混合黄油以及通过酯交换反应生产但不含鱼油的产品进行比较，研究其效果。金黄叙利亚仓鼠食用与三种黄油产品之一混合的仓鼠饲料。喂养6周后，测定血浆、红细胞、肝脏、大脑和内脏脂肪的脂肪酸组成。摄入含鱼油的黄油产品会使血浆、红细胞和肝脏中的n-3 PUFA水平升高。n-3 PUFA在磷脂中的掺入量显著高于三酰甘油。结果表明，用少量鱼油富集混合黄油可作为提高生物组织中n-3 PUFA水平的一种替代方法。
