制备磷脂包被微泡的新方法。
Novel methods for preparing phospholipid coated microbubbles.
作者信息
Pancholi K P, Farook U, Moaleji R, Stride E, Edirisinghe M J
机构信息
Department of Mechanical Engineering, University College London, Torrington Place, London, UK.
出版信息
Eur Biophys J. 2008 Apr;37(4):515-20. doi: 10.1007/s00249-007-0211-x. Epub 2007 Aug 9.
Two new methods for preparing phospholipid coated microbubble suspensions are elucidated. Firstly, co-axial electrohydrodynamic atomisation was utilized to generate 3-7 microm diameter microbubbles. Secondly, a specially designed and constructed T-junction device was used to prepare monodisperse microbubbles. Characteristics of microbubbles prepared by these two methods are compared with those obtained by sonication of the phospholipid suspension.
阐述了两种制备磷脂包被微泡悬浮液的新方法。首先，利用同轴电流体动力雾化来产生直径为3-7微米的微泡。其次，使用专门设计和构建的T型接头装置来制备单分散微泡。将通过这两种方法制备的微泡的特性与通过磷脂悬浮液超声处理获得的微泡特性进行了比较。
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