Ferretti Stefania, Fornia Samanta, Ampollini Luca, Rusca Michele, Salsi Paolo, Vaglio Augusto, Cortellini Pietro
Operative Unit of Urology - University Hospital of Parma, Italy.
Acta Biomed. 2007;78(1):41-5.
We aim to report the results of the curative, non-palliative, treatment of resection of lung metastases that are secondary to renal cell carcinoma (RCC).
Between 1988 and 2004, a radical metastasectomy with curative purposes was performed in 20 (11 males and 9 females) patients with renal clear cell carcinoma (RCC) who had already undergone nephrectomy and subsequently metastasectomy of lung metastases. The mean age was 66,9 years (range 48-81 years).
the intraoperative mortality of patients undergoing surgical resection of lung metastases from RCC was 0%; 17 out of 20 patients returned at follow up; 9 patients died; the mean survival-time after nephrectomy was 64+/-42 months (range 7-132 months) and the mean survival-time after metastasectomy was 31+/-29 months (range 4-99 months); 4 out of 9 pts had pulmonary recurrence after surgery. 8 patients are still alive; the mean follow up after nephrectomy was 134+/-115 months (range 30-372 months) and 72+/-44 months (range 25-150 months) after metastasectomy. 1 out of 8 pts had a pulmonary recurrence that was treated by surgery.
the radical resection of lung metastases is a safe and effective treatment in selected RCC patients.
我们旨在报告对肾细胞癌(RCC)继发性肺转移瘤进行根治性而非姑息性切除治疗的结果。
1988年至2004年间,对20例(11例男性和9例女性)肾透明细胞癌(RCC)患者进行了根治性转移瘤切除术,这些患者已接受肾切除术并随后进行了肺转移瘤切除术。平均年龄为66.9岁(范围48 - 81岁)。
接受RCC肺转移瘤手术切除患者的术中死亡率为0%;20例患者中有17例在随访时返回;9例患者死亡;肾切除术后的平均生存时间为64±42个月(范围7 - 132个月),转移瘤切除术后的平均生存时间为31±29个月(范围4 - 99个月);9例患者中有4例术后出现肺部复发。8例患者仍存活;肾切除术后的平均随访时间为134±115个月(范围30 - 372个月),转移瘤切除术后为72±44个月(范围25 - 150个月)。8例患者中有1例出现肺部复发,通过手术进行了治疗。
对于选定的RCC患者,肺转移瘤的根治性切除是一种安全有效的治疗方法。