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[普尔夏视网膜病变及类普尔夏视网膜病变的发病机制]

[Pathogenesis of Purtscher's retinopathy and Purtscher-like retinopathy].

作者信息

Holak Heinrich, Holak Nikolai, Huzarska Małgorzata, Holak Sophie

机构信息

Kliniki Okulistycznej w Centrum Medycznym im. Rudolfa Virchowa w Salzgitter.

出版信息

Klin Oczna. 2007;109(1-3):38-45.

Abstract

PURPOSE

The pathogenesis of Purtscher's retinopathy (PR) or Purtscher-like retinopathy (PIR) is illustrated on two case reports.

MATERIAL AND METHODS

Five patients with PR or PIR were examined ophthalmologically. Fluorescein angiography, fundus photography, visual field testing, and electroretinography were also performed.

RESULTS

In three cases, the PIR was observed after acute pancreatitis, in one case it arosed from cryoglobulinemy, because of hepatitis C, and in one case it was due to a classic PR after the thorax trauma. In the case of a slow resolution of retinal edema, atrophy of the retinal pigment epithelium and optic nerve, occurred. The therapy has been based on the internal medicine treatment of the causal disease and the administration of corticosteroids, to reduce retinal edema.

CONCLUSIONS

PR and PIR are interdisciplinary diseases caused by microembolization of retinal vessels. If changes are intensive and long lasting, visual prognosis is poor.

摘要

目的

通过两例病例报告阐述普尔夏视网膜病变(PR)或类普尔夏视网膜病变(PIR)的发病机制。

材料与方法

对5例PR或PIR患者进行眼科检查。还进行了荧光素血管造影、眼底摄影、视野测试和视网膜电图检查。

结果

3例PIR在急性胰腺炎后出现,1例因丙型肝炎导致冷球蛋白血症引发,1例因胸部外伤后出现典型PR。在视网膜水肿消退缓慢的情况下,发生了视网膜色素上皮和视神经萎缩。治疗基于对病因疾病的内科治疗以及使用皮质类固醇以减轻视网膜水肿。

结论

PR和PIR是由视网膜血管微栓塞引起的跨学科疾病。如果病变严重且持续时间长,视觉预后较差。

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