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管理脆性骨折患者的骨质疏松症:英国骨科协会指南有何影响?

Managing osteoporosis in patients with fragility fractures: did the British Orthopaedic Association guidelines have any impact?

作者信息

Nixon M F, Ibrahim T, Johari Y, Eltayef S, Hariharan D, Taylor G J

机构信息

Department of Orthopaedic Surgery, University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, Leicester, UK.

出版信息

Ann R Coll Surg Engl. 2007 Jul;89(5):504-9. doi: 10.1308/003588407X187630.

Abstract

INTRODUCTION

The incidence of fragility fractures could double in the next 50 years. Effective treatments for osteoporosis exist and the British Orthopaedic Association (BOA) has guidelines governing how to manage underlying osteoporosis in patients with fragility fractures. This study assessed how well two trauma units treat underlying osteoporosis and whether the BOA guidelines made any impact.

PATIENTS AND METHODS

Case notes of patients with a fracture of their proximal femur admitted during January and February in 2003, 2004 and 2005 were reviewed. The results were analysed for differences between site and year.

RESULTS

A total of 602 case notes were reviewed. There was a significant difference in the number of patients discharged on osteoporosis medication between the two sites (27% at LRI, 8% at KGH; P < 0.001), but not between 2003 and 2005 (22% and 16%; P = 0.16). Of the patients started on treatment, 83% were started on calcium and/or vitamin D(3) supplements.

CONCLUSIONS

The number of patients who had their underlying osteoporosis addressed was low and the type of treatment sub-optimal. This suggests the BOA guidelines have not made an impact and further work is required to improve the management of these patients.

摘要

引言

在未来50年中,脆性骨折的发病率可能会翻倍。目前存在针对骨质疏松症的有效治疗方法,英国骨科协会(BOA)也制定了关于如何治疗脆性骨折患者潜在骨质疏松症的指南。本研究评估了两个创伤科对潜在骨质疏松症的治疗效果以及BOA指南是否产生了任何影响。

患者与方法

回顾了2003年、2004年和2005年1月及2月期间收治的股骨近端骨折患者的病历。分析结果以比较不同地点和年份之间的差异。

结果

共回顾了602份病历。两个地点之间出院时接受骨质疏松症药物治疗的患者数量存在显著差异(伦敦皇家自由医院为27%,国王乔治医院为8%;P < 0.001),但2003年至2005年之间无显著差异(分别为22%和16%;P = 0.16)。在开始接受治疗的患者中,83%开始服用钙和/或维生素D(3)补充剂。

结论

接受潜在骨质疏松症治疗的患者数量较少,且治疗类型欠佳。这表明BOA指南并未产生影响,需要进一步开展工作以改善这些患者的管理。

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