Sioulas Vasileios, Christodoulakos George, Lambrinoudaki Irene, Politi Ekaterini, Sergentanis Theodoros N, Creatsas George
Menopause Clinic, 2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieio Hospital, Athens, Greece.
Fertil Steril. 2008 Apr;89(4):1018-20. doi: 10.1016/j.fertnstert.2007.04.033. Epub 2007 Aug 8.
This study assesses the possible associations between postmenopausal therapy (hormone therapy, raloxifene, and tibolone) and E-cadherin expression in normal cervical Papanicolaou smears (squamous, glandular, and metaplastic cells). E-cadherin immunostaining was less intense in metaplastic cells of women on tibolone, whereas hormone therapy and raloxifene were not associated with altered E-cadherin expression.
本研究评估绝经后治疗（激素治疗、雷洛昔芬和替勃龙）与正常宫颈巴氏涂片（鳞状细胞、腺细胞和化生细胞）中E-钙黏蛋白表达之间可能存在的关联。在使用替勃龙的女性的化生细胞中，E-钙黏蛋白免疫染色强度较低，而激素治疗和雷洛昔芬与E-钙黏蛋白表达改变无关。
