BMP7: a new bone metastases prevention?
作者信息
Fournier Pierrick G J, Guise Theresa A
机构信息
Department of Internal Medicine, Division of Endocrinology and Metabolism, University of Virginia, PO Box 801419, Charlottesville, VA 22908-1419, USA.
出版信息
Am J Pathol. 2007 Sep;171(3):739-43. doi: 10.2353/ajpath.2007.070582. Epub 2007 Aug 9.
Abstract
摘要
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本文引用的文献
1
BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo.骨形态发生蛋白7（BMP7）是人类前列腺上皮内环境稳定的一种假定调节因子，在体内是前列腺癌骨转移的有效抑制剂。
Am J Pathol. 2007 Sep;171(3):1047-57. doi: 10.2353/ajpath.2007.070168.
2
Stable overexpression of Smad7 in human melanoma cells impairs bone metastasis.Smad7在人黑色素瘤细胞中的稳定过表达会损害骨转移。
Cancer Res. 2007 Mar 1;67(5):2317-24. doi: 10.1158/0008-5472.CAN-06-3950.
3
Cancer statistics, 2007.2007年癌症统计数据。
CA Cancer J Clin. 2007 Jan-Feb;57(1):43-66. doi: 10.3322/canjclin.57.1.43.
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Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-beta type I receptor kinase inhibitor.转化生长因子-βⅠ型受体激酶抑制剂对肺和骨转移的抑制作用
Cancer Res. 2006 Jul 1;66(13):6714-21. doi: 10.1158/0008-5472.CAN-05-3565.
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The logic of TGFbeta signaling.转化生长因子β信号传导的逻辑
FEBS Lett. 2006 May 22;580(12):2811-20. doi: 10.1016/j.febslet.2006.04.033. Epub 2006 Apr 21.
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The tumor suppressor Smad4 is required for transforming growth factor beta-induced epithelial to mesenchymal transition and bone metastasis of breast cancer cells.肿瘤抑制因子Smad4是转化生长因子β诱导乳腺癌细胞上皮-间质转化和骨转移所必需的。
Cancer Res. 2006 Feb 15;66(4):2202-9. doi: 10.1158/0008-5472.CAN-05-3560.
7
Influence of BMPs on the formation of osteoblastic lesions in metastatic prostate cancer.骨形态发生蛋白对转移性前列腺癌中成骨细胞性病变形成的影响。
J Bone Miner Res. 2005 Dec;20(12):2189-99. doi: 10.1359/JBMR.050802. Epub 2005 Aug 1.
8
Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway.由Smad肿瘤抑制通路介导的乳腺癌骨转移。
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