赞比亚南部连续湿润和干旱年份中阿拉伯按蚊的时空遗传结构
Spatial and temporal genetic structure of Anopheles arabiensis in Southern Zambia over consecutive wet and drought years.
作者信息
Kent Rebekah J, Mharakurwa Sungano, Norris Douglas E
机构信息
The W. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
出版信息
Am J Trop Med Hyg. 2007 Aug;77(2):316-23.
No studies have addressed the spatial complexity of Anopheles arabiensis populations in Zambia or the effects of drought on the genetic structure of this species. We genotyped approximately 420 An. arabiensis at 12 microsatellite loci representing 18 collections from the Southern Province of Zambia. Collections spanned three transmission seasons and covered a wet year-drought year-wet year cycle. Anopheles arabiensis within the 2,000 km(2) of the Macha study region were panmictic, with high gene flow between Macha and Namwala, Zambia, which are 80 km apart. There was little evidence for genetic structuring among years, with no significant shifts in allele frequency distributions or observed heterozygosity, and no evidence for a genetic bottleneck despite a drastic reduction in mosquito numbers during the drought year. Anopheles arabiensis in southern Zambia has a large deme size, and the regional genetic structure of this species was little affected by an extended drought period.
尚无研究探讨赞比亚阿拉伯按蚊种群的空间复杂性或干旱对该物种遗传结构的影响。我们对来自赞比亚南部省份的18个样本中约420只阿拉伯按蚊进行了12个微卫星位点的基因分型。样本采集跨越了三个传播季节，涵盖了一个湿润年-干旱年-湿润年的周期。在马查研究区域2000平方公里范围内的阿拉伯按蚊是随机交配的，在相距80公里的赞比亚马查和纳姆瓦拉之间存在高基因流。几乎没有证据表明年份间存在遗传结构，等位基因频率分布或观察到的杂合度没有显著变化，并且尽管干旱年份蚊子数量急剧减少，但也没有遗传瓶颈的证据。赞比亚南部的阿拉伯按蚊种群规模较大，该物种的区域遗传结构几乎未受长期干旱期的影响。
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