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[重症肌无力和非重症肌无力胸腺瘤患者的抗肌联蛋白抗体]

[Anti-Titin-antibodies at the patients with myasthenic and non-myasthenic thymoma].

作者信息

Vetshev P S, Sanadze A G, Sidnev D V, Ippolitov L I, Zhivotov V A, Ablitsov A Iu

出版信息

Khirurgiia (Mosk). 2007(6):53-6.

PMID:17690667
Abstract

Serum specimens from 52 myasthenic patients with thymoma of various histological characteristics and 4 patients with thymoma without myasthenia have tested for anti-Titin-antibodies titer. It has been demonstrated that organ-specific thymoma dominated at myasthenic patients, and organ-nonspecific thymoma - at the patients without myasthenia. There was no correlation between severe clinical symptoms and the level of anti-Titin-antibodies. The titer of antibodies at the patients with organ-specific thymoma was higher that at ones with organ-nonspecific thymoma, but there was no correlation between the level of anti-Titin-antibodies and histological type of organ-specific thymoma.

摘要

对52例具有不同组织学特征的胸腺瘤型重症肌无力患者和4例无肌无力的胸腺瘤患者的血清标本进行了抗肌联蛋白抗体滴度检测。结果表明,重症肌无力患者中器官特异性胸腺瘤占主导,而无肌无力患者中则以器官非特异性胸腺瘤为主。严重临床症状与抗肌联蛋白抗体水平之间无相关性。器官特异性胸腺瘤患者的抗体滴度高于器官非特异性胸腺瘤患者,但抗肌联蛋白抗体水平与器官特异性胸腺瘤的组织学类型之间无相关性。

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Khirurgiia (Mosk). 2007(6):53-6.
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