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一例单侧半球脑炎病例。

A case of unilateral hemispheric encephalitis.

作者信息

Heo S H, Lee M-S, Ahn T B, Park K C, Yoon S S, Chang D I, Chung K C

机构信息

Department of Neurology, Kyung Hee University College of Medicine, #1 Hoegi-dong, Dongdaemun-gu, Seoul, 130-702, Korea.

出版信息

Neurol Sci. 2007 Aug;28(4):185-7. doi: 10.1007/s10072-007-0818-9. Epub 2007 Aug 10.

DOI:10.1007/s10072-007-0818-9
PMID:17690849
Abstract

Herein we report a case of encephalitis involving the unilateral hemisphere, with a clinical course different from that of Rasmussen syndrome. A 44-year-old man visited us because of headache and language abnormality. Cerebrospinal fluid examination showed lymphocytosis with increased level of protein. Brain MRI showed abnormal findings limited to the unilateral hemisphere. The symptoms and signs improved without any specific antiviral treatment in a week. However, language disturbance and right hemiparesis developed after a week. Steroid therapy was effective. He recovered without any neurologic sequelae. Our case was unusual encephalitis involving the unilateral hemisphere, which was benign and steroid-responsive.

摘要

在此,我们报告一例累及单侧半球的脑炎病例,其临床病程与拉斯穆森综合征不同。一名44岁男性因头痛和语言异常前来就诊。脑脊液检查显示淋巴细胞增多且蛋白水平升高。脑部MRI显示异常发现局限于单侧半球。未经任何特异性抗病毒治疗,症状和体征在一周内有所改善。然而,一周后出现了语言障碍和右侧偏瘫。类固醇治疗有效。他康复后未留下任何神经后遗症。我们的病例是累及单侧半球的罕见脑炎,为良性且对类固醇治疗有反应。

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本文引用的文献

1
Comparative immunopathogenesis of acute disseminated encephalomyelitis, neuromyelitis optica, and multiple sclerosis.急性播散性脑脊髓炎、视神经脊髓炎和多发性硬化症的比较免疫发病机制
Curr Opin Neurol. 2007 Jun;20(3):343-50. doi: 10.1097/WCO.0b013e3280be58d8.
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Acute disseminated encephalomyelitis: an update.急性播散性脑脊髓炎:最新进展
Arch Neurol. 2005 Nov;62(11):1673-80. doi: 10.1001/archneur.62.11.1673.
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Rasmussen's syndrome: progressive autoimmune multi-focal encephalopathy.拉斯穆森综合征:进行性自身免疫性多灶性脑病。
Pediatr Neurol. 2005 May;32(5):295-9. doi: 10.1016/j.pediatrneurol.2004.12.002.
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The level of nitric oxide in the cortex correlates well with brain lateralization.皮质中一氧化氮的水平与大脑偏侧化密切相关。
Neuroreport. 2004 Jun 28;15(9):1465-8. doi: 10.1097/01.wnr.0000130540.22012.77.
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Influenza-associated encephalitis/encephalopathy with a reversible lesion in the splenium of the corpus callosum: a case report and literature review.伴有胼胝体压部可逆性病变的流感相关性脑炎/脑病:一例报告及文献综述
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Rasmussen's syndrome.拉斯姆森综合征
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Brain diffusion after single seizures.单次癫痫发作后的脑扩散
Epilepsia. 2003 Jan;44(1):54-63. doi: 10.1046/j.1528-1157.2003.07802.x.
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Brain interleukin asymmetries and paw preference in mice.小鼠大脑白介素不对称性与爪偏好
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