视神经脊髓炎（Devic病）对利妥昔单抗治疗的反应各异。
Variable responses to rituximab treatment in neuromyelitis optica (Devic's disease).
作者信息
Capobianco M, Malucchi S, di Sapio A, Gilli F, Sala A, Bottero R, Marnetto F, Doriguzzi Bozzo C, Bertolotto A
机构信息
Centro di Riferimento Regionale Sclerosi Multipla & Neurobiologia Clinica - ASO S. Luigi Gonzaga, Regione Gonzole 10, I-10043, Orbassano (TO), Italy.
出版信息
Neurol Sci. 2007 Aug;28(4):209-11. doi: 10.1007/s10072-007-0823-z. Epub 2007 Aug 10.
PMID:17690854
Abstract
We have described two cases of Devic's disease patients treated with rituximab with different outcomes. The results indicate that there may be early unresponsiveness in very aggressive cases. Well designed clinical trials are needed to assess treatment effects in such a rare disease.
摘要
我们描述了两例使用利妥昔单抗治疗的视神经脊髓炎患者，结果各异。结果表明，在病情非常严重的病例中可能存在早期无反应情况。需要精心设计的临床试验来评估这种罕见疾病的治疗效果。
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