Kuklina Elena V, Whiteman Maura K, Hillis Susan D, Jamieson Denise J, Meikle Susan F, Posner Samuel F, Marchbanks Polly A
Quantell Inc., Taneytown, MD, USA.
Matern Child Health J. 2008 Jul;12(4):469-77. doi: 10.1007/s10995-007-0256-6. Epub 2007 Aug 10.
The accuracy of maternal morbidity estimates from hospital discharge data may be influenced by incomplete identification of deliveries. In maternal/infant health studies, obstetric deliveries are often identified only by the maternal outcome of delivery code (International Classification of Diseases code = V27). We developed an enhanced delivery identification method based on additional delivery-related codes and compared the performance of the enhanced method with the V27 method in identifying estimates of deliveries as well as estimates of maternal morbidity.
The enhanced and standard V27 methods for identifying deliveries were applied to data from the 1998-2004 Healthcare Cost and Utilization Project Nationwide Inpatient Sample, an annual nationwide representative survey of U.S. hospitalizations. Odds ratios (ORs) and 95% confidence intervals (CIs) from logistic regression were used to examine predictors of deliveries not identified using the V27 method.
The enhanced method identified 958,868 (3.4%) more deliveries than the 27,128,539 identified using the V27 code alone. Severe complications including major puerperal infections (OR = 3.1, 95% CI 2.8-3.4), hysterectomy (OR = 6.0, 95% CI 5.3-6.8), sepsis (OR = 11.9, 95% CI 10.3-13.6) and respiratory distress syndrome (OR = 16.6, 95% CI 14.4-19.2) were strongly associated with deliveries not identified by the V27 method. Nationwide prevalence rates of severe maternal complications were underestimated with the V27 method compared to the enhanced method, ranging from 9% underestimation for major puerperal infections to 40% underestimation for respiratory distress syndrome.
Deliveries with severe obstetric complications may be more likely to be missed using the V27 code. Researchers should be aware that selecting deliveries from hospital stay records by V27 codes alone may affect the accuracy of their findings.
利用医院出院数据估算孕产妇发病率的准确性可能会受到分娩识别不完整的影响。在母婴健康研究中,产科分娩往往仅通过分娩结局代码(国际疾病分类代码=V27)来识别。我们基于额外的分娩相关代码开发了一种强化分娩识别方法,并比较了该强化方法与V27方法在识别分娩估算以及孕产妇发病率估算方面的表现。
将强化和标准的V27分娩识别方法应用于1998 - 2004年医疗成本与利用项目全国住院患者样本的数据,这是一项对美国住院情况进行的年度全国代表性调查。采用逻辑回归的比值比(OR)和95%置信区间(CI)来检验未使用V27方法识别的分娩的预测因素。
强化方法比仅使用V27代码识别的27128539例分娩多识别出958868例(3.4%)。严重并发症包括产褥期严重感染(OR = 3.1,95% CI 2.8 - 3.4)、子宫切除术(OR = 6.0,95% CI 5.3 - 6.8)、败血症(OR = 11.9,95% CI 10.3 - 13.6)和呼吸窘迫综合征(OR = 16.6,95% CI 14.4 - 19.2)与未被V27方法识别的分娩密切相关。与强化方法相比,V27方法低估了严重孕产妇并发症的全国患病率,从产褥期严重感染的9%低估到呼吸窘迫综合征的40%低估。
使用V27代码可能更容易遗漏伴有严重产科并发症的分娩。研究人员应意识到,仅通过V27代码从住院记录中选择分娩病例可能会影响研究结果的准确性。