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2007 - 2014年严重孕产妇发病率及产科分娩麻醉技术中的种族和民族差异:一项多州分析

Racial and ethnic disparities in severe maternal morbidity and anesthetic techniques for obstetric deliveries: A multi-state analysis, 2007-2014.

作者信息

Tangel Virginia E, Matthews Kathy C, Abramovitz Sharon E, White Robert S

机构信息

Weill Cornell Medicine, Center for Perioperative Outcomes, Department of Anesthesiology, 428 East 72nd Street, Suite 800A, New York, NY 10021, United States of America.

Weill Cornell Medicine, Department of Obstetrics and Gynecology, 525 East 68th Street, New York, NY 10065, United States of America.

出版信息

J Clin Anesth. 2020 Oct;65:109821. doi: 10.1016/j.jclinane.2020.109821. Epub 2020 May 12.

Abstract

STUDY OBJECTIVE

To evaluate racial and ethnic disparities in severe maternal morbidity (SMM) and administered anesthesia techniques.

DESIGN

Retrospective cohort study.

SETTING

Administrative database study using 2007-2014 data from California, Florida, New York, Maryland, and Kentucky from the State Inpatient Databases (SID), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality (AHRQ).

PATIENTS

6,879,332 parturients aged ≥18 years old who underwent deliveries were identified by International Classification of Disease, 9th Revision, Clinical Modification (ICD-9-CM) codes: V27.0 and V27.1 for singleton deliveries, and V27.2 through V27.8 for multiple births.

INTERVENTIONS

Patients who had a singleton or multiple delivery.

MEASUREMENTS

Patients were cohorted by race/ethnicity: white (reference category), black, Hispanic, other, or missing. Demographic characteristics and comorbidities were compared. Adjusted odds ratios with generalized linear mixed modeling were calculated for SMM. We also conducted additional exploratory analyses of racial/ethnic disparities in the anesthesia technique used for cesarean deliveries, as well as the use of analgesia in vaginal deliveries.

MAIN RESULTS

When controlling for patient demographics, comorbidities, and hospital characteristics, black women were more likely than white women to experience any SMM (adjusted odds ratio: 1.38, 95% CI: 1.35-1.41). This finding was consistent in stratified analyses. Black women were also more likely than white women to receive general anesthesia for cesarean delivery (aOR: 1.44, 95% CI: 1.39-1.49) and to receive no analgesia for vaginal delivery (aOR: 1.45, 95% CI: 1.43-1.47).

CONCLUSIONS

Our findings highlight the differences in outcomes and care for black as compared to white parturients related to SMM and administered anesthesia techniques.

摘要

研究目的

评估严重孕产妇发病率(SMM)和麻醉技术应用方面的种族和民族差异。

设计

回顾性队列研究。

研究地点

利用来自加利福尼亚州、佛罗里达州、纽约州、马里兰州和肯塔基州2007 - 2014年数据的行政数据库研究,数据来自州住院病人数据库(SID)、医疗保健成本与利用项目(HCUP)、医疗保健研究与质量机构(AHRQ)。

患者

通过国际疾病分类第九版临床修订本(ICD - 9 - CM)编码识别出6,879,332名年龄≥18岁的产妇,其中单胎分娩的编码为V27.0和V27.1,多胎分娩的编码为V27.2至V27.8。

干预措施

进行单胎或多胎分娩的患者。

测量指标

患者按种族/民族分组:白人(参照组)、黑人、西班牙裔、其他或缺失。比较人口统计学特征和合并症。采用广义线性混合模型计算SMM的调整优势比。我们还对剖宫产所用麻醉技术以及阴道分娩中镇痛药物使用方面的种族/民族差异进行了额外的探索性分析。

主要结果

在控制患者人口统计学特征、合并症和医院特征后,黑人女性比白人女性更易发生任何严重孕产妇发病情况(调整优势比:1.38,95%置信区间:1.35 - 1.41)。这一发现在分层分析中一致。黑人女性剖宫产接受全身麻醉的可能性也高于白人女性(调整后优势比:1.44,95%置信区间:1.39 - 1.49),且阴道分娩未接受镇痛的可能性也高于白人女性(调整后优势比:1.45,95%置信区间:1.43 - 1.47)。

结论

我们的研究结果突出了与白人产妇相比,黑人产妇在严重孕产妇发病情况及麻醉技术应用方面的结局和护理差异。

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