Gray Kylie M, Tonge Bruce J, Sweeney Deborah J
Centre for Developmental Psychiatry and Psychology, School of Psychology, Psychiatry and Psychological Medicine, Monash University, 246 Clayton Road, Clayton, Victoria, Australia.
J Autism Dev Disord. 2008 Apr;38(4):657-67. doi: 10.1007/s10803-007-0432-y. Epub 2007 Aug 10.
Few studies have focused on the validity of the ADI-R and ADOS in the assessment of preschool children with developmental delay. This study aimed to evaluate the diagnostic validity of the ADI-R and the ADOS in young children. Two-hundred and nine children aged 20-55 months participated in the study, 120 of whom received a diagnosis of autism. ADI-R and ADOS diagnostic classifications were compared to consensus clinical diagnoses. Children with a clinical diagnosis of autism scored significantly higher on all algorithm domains of the ADI-R and ADOS. The ADOS performed better than the ADI-R in comparison to consensus clinical diagnosis. Characteristics of the ADI-R and ADOS false positive and false negative cases are explored. Further research is recommended in terms of examining which items of the ADI-R best predict a diagnosis of autism for very young children with developmental problems.
很少有研究关注孤独症诊断访谈修订版（ADI-R）和孤独症诊断观察量表（ADOS）在评估发育迟缓学龄前儿童时的效度。本研究旨在评估ADI-R和ADOS在幼儿中的诊断效度。209名年龄在20至55个月的儿童参与了该研究，其中120名被诊断为孤独症。将ADI-R和ADOS的诊断分类与共识临床诊断进行比较。临床诊断为孤独症的儿童在ADI-R和ADOS的所有算法领域得分显著更高。与共识临床诊断相比，ADOS的表现优于ADI-R。探讨了ADI-R和ADOS假阳性和假阴性病例的特征。建议进一步研究以确定ADI-R的哪些项目最能预测有发育问题的非常年幼儿童的孤独症诊断。
