Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill, Campus Box #7255, Chapel Hill, NC, 27599-7255, USA.
Department of Biostatistics, Collaborative Studies Coordinating Center, University of North Carolina at Chapel Hill, Campus Box #8030, Chapel Hill, NC, 27516, USA.
J Autism Dev Disord. 2021 Oct;51(10):3456-3468. doi: 10.1007/s10803-020-04776-x. Epub 2021 Jan 2.
Prior studies investigating restricted and repetitive behavior (RRB) subtypes within autism spectrum disorder (ASD) have found varied factor structures for symptom groupings, in part, due to variation in symptom measurement and broad sample age ranges. This study examined RRBs among 827 preschool-age children, ages 35 to 71 months, through an exploratory factor analysis of RRB items from the Autism Diagnostic Interview-Revised (ADI-R) collected through the Study to Explore Early Development. The factor structures of RRBs among children with confirmed ASD versus those with non-autism developmental concerns were qualitatively compared. Correlations between RRB factors and participant characteristics were examined in the ASD group. Three conceptually well-defined factors characterized as repetitive sensorimotor behaviors (RSMB), insistence on sameness (IS), and a novel stereotyped speech (SPEECH) factor emerged for the ASD group only. Distinct factors were supported by different clinical correlates. Findings have implications for improving differential diagnosis and understanding of ASD symptomatology in this age range.
先前的研究调查了自闭症谱系障碍(ASD)中的受限和重复行为(RRB)亚型,发现症状分组的因素结构各不相同,部分原因是症状测量和广泛的样本年龄范围的差异。本研究通过对通过探索早期发展研究收集的自闭症诊断访谈修订版(ADI-R)中的 RRB 项目进行探索性因素分析,检查了 827 名 35 至 71 个月大的学龄前儿童的 RRB。比较了具有确诊 ASD 儿童和具有非自闭症发育问题儿童的 RRB 因子结构。在 ASD 组中,检查了 RRB 因子与参与者特征之间的相关性。对于 ASD 组,仅出现了三个概念上定义明确的因子,分别为重复感觉运动行为(RSMB)、坚持不变(IS)和新颖的刻板言语(SPEECH)因子。不同的因子由不同的临床相关性支持。这些发现对改善该年龄段的鉴别诊断和理解 ASD 症状学具有重要意义。