• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Increased concentrations of endogenous 13-cis- and all-trans-retinoic acids in diffuse idiopathic skeletal hyperostosis, as demonstrated by HPLC.

作者信息

Periquet B, Lambert W, Garcia J, Lecomte G, De Leenheer A P, Mazieres B, Thouvenot J P, Arlet J

机构信息

Laboratorie de Biochimie, CHU Purpan, Toulouse, France.

出版信息

Clin Chim Acta. 1991 Nov 9;203(1):57-65. doi: 10.1016/0009-8981(91)90156-7.

DOI:10.1016/0009-8981(91)90156-7
PMID:1769121
Abstract

Endogenous 13-cis- and all-trans-retinoic acids have been quantitated in human serum using a solvent extraction procedure followed by isocratic reversed phase high performance liquid chromatography and UV detection. In healthy adults, after an overnight fasting period, the concentrations of 13-cis- and all-trans-retinoic acids yielded 5.3 +/- 2.43 nmol/l and 11.8 +/- 3.3 nmol/l, respectively (mean +/- SD). The method has been successfully applied to the analysis of both isomers in serum from patients with idiopathic skeletal hyperostosis in whom, the 13-cis- as well as all-trans-retinoic acid levels were raised as compared to the control group.

摘要

相似文献

1
Increased concentrations of endogenous 13-cis- and all-trans-retinoic acids in diffuse idiopathic skeletal hyperostosis, as demonstrated by HPLC.
Clin Chim Acta. 1991 Nov 9;203(1):57-65. doi: 10.1016/0009-8981(91)90156-7.
2
Simultaneous determination of endogenous retinoic acid isomers and retinol in human plasma by isocratic normal-phase HPLC with ultraviolet detection.
Clin Chem. 1994 Jan;40(1):48-57.
3
Simultaneous analysis of retinol, all-trans- and 13-cis-retinoic acid and 13-cis-4-oxoretinoic acid in plasma by liquid chromatography using on-column concentration after single-phase fluid extraction.采用单相流体萃取后柱上富集的液相色谱法同时分析血浆中的视黄醇、全反式和13-顺式视黄酸以及13-顺式-4-氧代视黄酸。
J Chromatogr B Biomed Sci Appl. 1997 Jun 20;694(1):83-92. doi: 10.1016/s0378-4347(97)00109-6.
4
Simultaneous determination of all-trans and 13-cis retinoic acids and their 4-oxo metabolites by adsorption liquid chromatography after solid-phase extraction.
J Chromatogr B Biomed Appl. 1995 Apr 7;666(1):55-61. doi: 10.1016/0378-4347(94)00554-i.
5
Identification and quantitation of all-trans- and 13-cis-retinoic acid and 13-cis-4-oxoretinoic acid in human plasma.人血浆中全反式维甲酸、13-顺式维甲酸和13-顺式-4-氧代维甲酸的鉴定与定量分析。
J Lipid Res. 1990 Aug;31(8):1445-54.
6
Determination of endogenous levels of 13-cis-retinoic acid (isotretinoin), all-trans-retinoic acid (tretinoin) and their 4-oxo metabolites in human and animal plasma by high-performance liquid chromatography with automated column switching and ultraviolet detection.采用高效液相色谱法结合自动柱切换和紫外检测测定人和动物血浆中内源性13-顺式维甲酸（异维甲酸）、全反式维甲酸（维甲酸）及其4-氧代代谢物的水平。
J Chromatogr B Biomed Sci Appl. 1997 Oct 24;700(1-2):31-47. doi: 10.1016/s0378-4347(97)00303-4.
7
A sensitive high-pressure liquid chromatography/particle beam/mass spectrometry assay for the determination of all-trans-retinoic acid and 13-cis-retinoic acid in human plasma.一种用于测定人血浆中全反式维甲酸和13-顺式维甲酸的灵敏的高压液相色谱/粒子束/质谱分析法。
J Pharm Sci. 1996 Mar;85(3):287-90. doi: 10.1021/js950339x.
8
13-cis-retinoic acid is an endogenous compound in human serum.13-顺式维甲酸是人体血清中的一种内源性化合物。
J Lipid Res. 1990 Feb;31(2):175-82.
9
Biological variation of retinoids in man.
Scand J Clin Lab Invest. 2002;62(7):511-9. doi: 10.1080/003655102321004521.
10
Vitamin A supplementation increases levels of retinoic acid compounds in human plasma: possible implications for teratogenesis.补充维生素A可提高人体血浆中视黄酸化合物的水平：对致畸作用可能产生的影响。
Arch Toxicol. 1990;64(6):502-3. doi: 10.1007/BF01977634.