Green D E
Ann N Y Acad Sci. 1975 Dec 30;264:61-82. doi: 10.1111/j.1749-6632.1975.tb31475.x.
If, as we deem inevitable, the principles of energy coupling are universal, then the necessity for charge-separating devices will apply across the board to all bioenergetic systems. Since, apart from the elctron transfer chain, ionophores are the only charge-separating devices available in bioenergetic systems, model of energy coupling that does not feature this central role of ionophores can be taken seriously. The ionophore approach thus opens the royal highway to the ultimate solution of all bioenergetic problems.
如果正如我们认为不可避免的那样，能量偶联原理具有普遍性，那么电荷分离装置的必要性将全面适用于所有生物能量系统。由于除了电子传递链之外，离子载体是生物能量系统中仅有的电荷分离装置，因此那些没有突出离子载体核心作用的能量偶联模型就值得认真对待了。离子载体方法因此为所有生物能量问题的最终解决开辟了康庄大道。
