金黄色葡萄球菌致病岛SaPI1的转导颗粒由辅助噬菌体编码的蛋白质组成。
Transducing particles of Staphylococcus aureus pathogenicity island SaPI1 are comprised of helper phage-encoded proteins.
作者信息
Tallent Sandra M, Langston Timothy B, Moran Richard G, Christie Gail E
机构信息
Department of Microbiology and Immunology, VCU, Richmond, VA 23298-0678, USA.
出版信息
J Bacteriol. 2007 Oct;189(20):7520-4. doi: 10.1128/JB.00738-07. Epub 2007 Aug 10.
Abstract
The relationship between the composition of SaPI1 transducing particles and those of helper phage 80alpha was investigated by direct comparison of virion proteins. Twelve virion proteins were identified by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and mass spectrometry; all were present in both 80alpha and SaPI1 virions, and all were encoded by 80alpha. No SaPI1-encoded proteins were detected. This confirms the prediction that SaPI1 is encapsidated in a virion assembled from helper phage-encoded proteins.
摘要
通过对病毒粒子蛋白的直接比较，研究了SaPI1转导颗粒与辅助噬菌体80α的组成之间的关系。通过十二烷基硫酸钠-聚丙烯酰胺凝胶电泳和质谱法鉴定了12种病毒粒子蛋白；所有这些蛋白都同时存在于80α和SaPI1病毒粒子中，并且全部由80α编码。未检测到SaPI1编码的蛋白。这证实了SaPI1被包裹在由辅助噬菌体编码的蛋白组装而成的病毒粒子中的预测。
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